Zheng Haixiang, Vidili Gianpaolo, Casu Gavino, Navarese Eliano Pio, Sechi Leonardo A, Chen Youren
Department of Cardiology, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Front Toxicol. 2024 Oct 10;6:1479292. doi: 10.3389/ftox.2024.1479292. eCollection 2024.
With the widespread use of plastic products and the increase in waste, microplastics and nanoplastics (MNPs) have become an important issue in global environmental pollution. In recent years, an increasing number of studies have shown that MNPs may have negative impacts on human health. This review aimed to explore the association between MNPs and cardiovascular disease and provide an outlook for future research. Research has shown that there may be a link between MNPs exposure and cardiovascular disease. Laboratory studies have shown that animals exposed to MNPs often exhibit abnormalities in the cardiovascular system, such as increased blood pressure, vascular inflammation, and myocardial damage. Epidemiological surveys have also revealed that people exposed to MNPs are more likely to suffer from cardiovascular diseases, such as hypertension and myocardial infarction. Although the specific impact mechanism is not fully understood, there are several possible pathways of action, including the effects of toxic substances on MNPs and interference with the endocrine system. In summary, MNPs exposure may have a negative impact on cardiovascular health, but further research is needed to confirm its specific mechanism and extent of impact to guide relevant public health and environmental policies.
随着塑料制品的广泛使用和废弃物的增加,微塑料和纳米塑料(MNPs)已成为全球环境污染中的一个重要问题。近年来,越来越多的研究表明,MNPs可能对人类健康产生负面影响。本综述旨在探讨MNPs与心血管疾病之间的关联,并为未来研究提供展望。研究表明,MNPs暴露与心血管疾病之间可能存在联系。实验室研究表明,接触MNPs的动物常常表现出心血管系统异常,如血压升高、血管炎症和心肌损伤。流行病学调查也显示,接触MNPs的人更易患心血管疾病,如高血压和心肌梗死。尽管具体的影响机制尚未完全明确,但存在几种可能的作用途径,包括有毒物质对MNPs的影响以及对内分泌系统的干扰。总之,MNPs暴露可能对心血管健康产生负面影响,但需要进一步研究以确认其具体机制和影响程度,从而指导相关公共卫生和环境政策。