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癌症患者生命最后一年的医疗支出差异:基于登记的研究。

Differences in Health Care Expenditures by Cancer Patients During Their Last Year of Life: A Registry-Based Study.

机构信息

Department of Oncology-Pathology, Karolinska Institutet, Stockholms Sjukhem Foundation, Mariebergsgatan 22, SE 11219 Stockholm, Sweden.

Research and Development Department, Stockholm's Sjukhem Foundation, Mariebergsgatan 22, SE 11219 Stockholm, Sweden.

出版信息

Curr Oncol. 2024 Oct 16;31(10):6205-6217. doi: 10.3390/curroncol31100462.

Abstract

BACKGROUND

During the last year of life, persons with cancer should probably have similar care needs and costs, but studies suggest otherwise.

METHODS

A study of direct medical costs (excluding costs for expensive prescription drugs) was performed based on registry data in Stockholm County, which covers 2.4 million inhabitants, for all deceased persons with cancer during 2015-2021. The data were mainly analyzed with the aid of multiple regression models, including Generalized Linear Models (GLMs).

RESULTS

In a population of 20,431 deceased persons with cancer, the costs increased month by month ( < 0.0001). Higher costs were mainly associated with lower age ( < 0.0001), higher risk of frailty, as measured by the Hospital Frailty Risk Scale ( < 0.0001), and having a hematological malignancy. In a separate model, where those 5% with the highest costs were identified, these variables were strengthened. Sex and socio-economic groups on an area level had little or no significance. Systemic cancer treatments during the last month of life and acute hospitals as place of death had only a moderate impact on costs in adjusted models.

CONCLUSIONS

Higher costs are mainly related to lower age, higher frailty risk and having a hematological malignancy, and the effects are both statistically and clinically significant despite the fact that expensive drugs were not included. On the other hand, the costs were mainly comparable in regard to sex or socio-economic factors, indicating equal care.

摘要

背景

在生命的最后一年,癌症患者可能有类似的护理需求和费用,但研究表明并非如此。

方法

本研究基于斯德哥尔摩县的登记数据,对 2015 年至 2021 年期间所有去世的癌症患者的直接医疗费用(不包括昂贵处方药的费用)进行了研究。这些数据主要通过包括广义线性模型(GLM)在内的多项回归模型进行分析。

结果

在 20431 名去世的癌症患者中,费用逐月增加(<0.0001)。较高的费用主要与较低的年龄(<0.0001)、较高的脆弱性风险(由医院脆弱性风险量表衡量,<0.0001)以及患有血液恶性肿瘤有关。在另一个模型中,确定了费用最高的 5%的患者,这些变量得到了强化。性别和按地区划分的社会经济群体几乎没有或没有意义。在调整后的模型中,生命最后一个月的全身癌症治疗和急性医院作为死亡地点对费用只有适度影响。

结论

较高的费用主要与较低的年龄、较高的脆弱性风险和患有血液恶性肿瘤有关,尽管未包括昂贵的药物,但这些影响在统计学和临床上均具有显著意义。另一方面,费用在性别或社会经济因素方面主要相当,表明护理平等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df82/11505941/5920c5bf428e/curroncol-31-00462-g001.jpg

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