Rahman Taieba Tuba, Rahman Al Mazedur, Pei Zhijian, Wood Nathan, Qin Hongmin
Department of Industrial & Systems Engineering, Texas A&M University, College Station, TX 77843, USA.
Department of Biology, Texas A&M University, College Station, TX 77843, USA.
Biomimetics (Basel). 2024 Sep 29;9(10):589. doi: 10.3390/biomimetics9100589.
This study systematically investigates the effects of the coaxial nozzle's inner nozzle diameter on the strength and gelation of filaments produced via extrusion-based 3D printing with in situ ionic crosslinking. In this system, bioink (sodium alginate solution) was extruded through the outer nozzle, and the ionic crosslinking solution (calcium chloride solution) was extruded through the inner nozzle. The outer nozzle diameter was fixed at 2.16 mm, and the inner nozzle diameter was varied among 1.19, 0.84, and 0.584 mm. The results indicate that, as the inner nozzle diameter decreased, filament strength decreased, and filament gelation became poorer. These findings highlight the importance of optimizing inner nozzle diameter for improved filament strength and gelation in extrusion-based 3D printing with in situ ionic crosslinking.
本研究系统地研究了同轴喷嘴的内喷嘴直径对通过基于挤出的原位离子交联3D打印生产的长丝强度和凝胶化的影响。在该系统中,生物墨水(海藻酸钠溶液)通过外喷嘴挤出,离子交联溶液(氯化钙溶液)通过内喷嘴挤出。外喷嘴直径固定为2.16mm,内喷嘴直径在1.19、0.84和0.584mm之间变化。结果表明,随着内喷嘴直径减小,长丝强度降低,长丝凝胶化变差。这些发现突出了优化内喷嘴直径对于在基于挤出的原位离子交联3D打印中提高长丝强度和凝胶化的重要性。