Păsăran Emilia-Daniela, Opriș-Belinski Daniela, Berghea Florian, Orzan Olguța Anca, Oancea Corina, Bojincă Violeta-Claudia, Bojincă Mihai, Mardale Denise-Ani, Saulescu Ioana Cristina, Bălănescu Andra-Rodica
Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Internal Medicine and Rheumatology, 'Sf. Maria' Clinical Hospital, 011192 Bucharest, Romania.
Clin Pract. 2024 Oct 16;14(5):2125-2138. doi: 10.3390/clinpract14050168.
BACKGROUND/OBJECTIVES: Psoriasis is a chronic inflammatory condition mediated by the immune system with various manifestations. The increased prevalence of subclinical joint involvement has led to the development of early diagnostic methods for psoriatic arthritis, including several instruments that have been validated and used in clinical practice. The aim of this study was to perform the Romanian translation, cultural adaptation, and validation of three assessment tools: the Early Arthritis for Psoriatic Patients (EARP) Questionnaire, Psoriasis Epidemiology Screening Tool (PEST), and Toronto Psoriatic Arthritis Screen 2 (TOPAS 2), which are designed to evaluate early-stage arthritis in patients with psoriasis.
All the activities were carried out in accordance with the internationally recognized methodology recommended by the International Society for Pharmacoeconomics and Outcome Research (ISPOR), the recommendations of the World Health Organization (WHO) regarding the translation process and the validation of instruments, and data from the international literature. These three questionnaires were administered to 29 patients with psoriasis diagnosed by biopsy. A descriptive study was conducted and the data were analyzed with appropriate statistical tests using the PSPP program. A reliability test was assessed using Cronbach's alpha coefficient.
The obtained values were significant for the first two questionnaires, with a value of 0.89 for the EARP and 0.63 for the PEST, but the value was not as significant for ToPAS2, at 0.40.
This pilot study revealed that the Romanian and original versions of the three questionnaires are similar.
背景/目的:银屑病是一种由免疫系统介导的慢性炎症性疾病,有多种表现形式。亚临床关节受累患病率的增加促使了银屑病关节炎早期诊断方法的发展,包括几种已在临床实践中得到验证和应用的工具。本研究的目的是对三种评估工具进行罗马尼亚语翻译、文化调适和验证,这三种工具分别是银屑病患者早期关节炎(EARP)问卷、银屑病流行病学筛查工具(PEST)和多伦多银屑病关节炎筛查2(TOPAS 2),旨在评估银屑病患者的早期关节炎。
所有活动均按照国际药物经济学和结果研究协会(ISPOR)推荐的国际认可方法、世界卫生组织(WHO)关于工具翻译过程和验证的建议以及国际文献数据进行。这三份问卷被发放给29名经活检确诊的银屑病患者。进行了描述性研究,并使用PSPP程序通过适当的统计检验对数据进行分析。使用克朗巴赫α系数评估可靠性测试。
前两份问卷获得的值具有显著性,EARP的值为0.89,PEST的值为0.63,但TOPAS 2的值不那么显著,为0.40。
这项初步研究表明,这三份问卷的罗马尼亚语版本和原始版本相似。