Balakin Evgenii, Yurku Ksenia, Fomina Tatiana, Butkova Tatiana, Nakhod Valeriya, Izotov Alexander, Kaysheva Anna, Pustovoyt Vasiliy
Federal Medical Biophysical Center of Federal Medical Biological Agency, 123098 Moscow, Russia.
Institute of Biomedical Chemistry, 119121 Moscow, Russia.
Biology (Basel). 2024 Oct 11;13(10):813. doi: 10.3390/biology13100813.
According to the Centers for Disease Control and Prevention (CDC), the national public health agency of the United States, traumatic brain injury is among the leading causes of mortality and disability worldwide. The consequences of TBI include diffuse brain atrophy, local post-traumatic atrophy, arachnoiditis, pachymeningitis, meningocerebral cicatrices, cranial nerve lesions, and cranial defects. In 2019, the economic cost of injuries in the USA alone was USD 4.2 trillion, which included USD 327 billion for medical care, USD 69 billion for work loss, and USD 3.8 trillion for the value of statistical life and quality of life losses. More than half of this cost (USD 2.4 trillion) was among working-age adults (25-64 years old). Currently, the development of new diagnostic approaches and the improvement of treatment techniques require further experimental studies focused on modeling TBI of varying severity.
根据美国国家公共卫生机构疾病控制与预防中心（CDC）的数据，创伤性脑损伤是全球死亡和残疾的主要原因之一。创伤性脑损伤的后果包括弥漫性脑萎缩、局部创伤后萎缩、蛛网膜炎、硬脑膜炎、脑膜脑瘢痕、颅神经损伤和颅骨缺损。2019年，仅美国的损伤经济成本就达4.2万亿美元，其中包括3270亿美元的医疗费用、690亿美元的工作损失以及3.8万亿美元的统计生命价值和生活质量损失。超过一半的成本（2.4万亿美元）发生在工作年龄成年人（25至64岁）中。目前，新诊断方法的开发和治疗技术的改进需要进一步开展实验研究，重点是对不同严重程度的创伤性脑损伤进行建模。
