Infante-Cano Marta, García-Muñoz Cristina, Matias-Soto Javier, Pineda-Escobar Saul, Villar-Alises Olga, Martinez-Calderon Javier
CTS 1110: Understanding Movement and Self in Health From Science (UMSS) Research Group, Andalusia, Spain.
Universidad Loyola de Andalucía, Seville, Spain.
Arch Womens Ment Health. 2025 Jun;28(3):475-489. doi: 10.1007/s00737-024-01526-1. Epub 2024 Oct 25.
To summarize the pooled prevalence rates of anxiety and depression in women with polycystic ovary syndrome.
An overview of systematic reviews with meta-analysis was conducted. The CINAHL, Embase, PsycINFO, and PubMed databases were searched up to April 22, 2024. The methodological quality of systematic reviews was assessed using AMSTAR 2. The degree of overlap between reviews was analyzed by calculating the corrected covered area.
Ten systematic reviews were selected. Regarding anxiety disorders, the pooled prevalence of panic disorder, social phobia, and anxiety disorders without specifying the type of disorder were 4%, 5%, and 16.9%, respectively. This prevalence was higher in depressive disorders, reaching 34.8%. Anxiety symptoms were very prevalent in women with PCOS, although the prevalence varied depending on the self-reported questionnaire used: the Hamilton Anxiety Scale 69.4%, the Hospital Anxiety and Depression Scale 41.5%, and the Self-rating Anxiety Scale 32.4%. Additionally, the highest prevalence of depression symptoms was associated with the Beck Depression Inventory 46.0%, followed by the Self-rating Depression Scale 39.2%, and the Hospital Anxiety and Depression Scale, which ranged from 31% to 33.8%.
Meta-analyses found mainly anxiety and depression symptoms and disorders are prevalent in women with PCOS. Meta-analyses also showed women with PCOS had a higher risk of having anxiety disorders, and depression symptoms than women without PCOS.
• Anxiety symptoms were prevalent, although the prevalence varied depending on the self-reported questionnaire. • The highest prevalence of depression symptoms was associated with the Beck Depression Inventory (46.0%). • The pooled prevalence of anxiety disorders without specifying the type of disorder was 16.9%.
总结多囊卵巢综合征女性焦虑和抑郁的合并患病率。
进行了一项带有荟萃分析的系统评价概述。截至2024年4月22日，检索了CINAHL、Embase、PsycINFO和PubMed数据库。使用AMSTAR 2评估系统评价的方法学质量。通过计算校正覆盖面积分析评价之间的重叠程度。
选择了10项系统评价。关于焦虑症，惊恐障碍、社交恐惧症以及未明确障碍类型的焦虑症的合并患病率分别为4%、5%和16.9%。抑郁症的患病率更高，达到34.8%。焦虑症状在多囊卵巢综合征女性中非常普遍，尽管患病率因所使用的自我报告问卷而异：汉密尔顿焦虑量表为69.4%，医院焦虑抑郁量表为41.5%，自评焦虑量表为32.4%。此外，抑郁症状的最高患病率与贝克抑郁量表相关，为46.0%，其次是自评抑郁量表，为39.2%，医院焦虑抑郁量表的患病率在31%至33.8%之间。
荟萃分析发现，焦虑和抑郁症状及障碍在多囊卵巢综合征女性中普遍存在。荟萃分析还表明，与没有多囊卵巢综合征的女性相比，患有多囊卵巢综合征的女性患焦虑症和抑郁症状的风险更高。
• 焦虑症状普遍存在，尽管患病率因自我报告问卷而异。• 抑郁症状的最高患病率与贝克抑郁量表相关（46.0%）。• 未明确障碍类型的焦虑症合并患病率为16.9%。
