文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

基于蛋白质的仿生方法制备的六种提取物的化学成分与抗氧化活性

Chemical Composition and Antioxidant Activity of Six Extracts Using Protein-Based Biomimetic Methods.

作者信息

Barbu Ioana Andreea, Toma Vlad Alexandru, Moț Augustin Cătălin, Vlase Ana-Maria, Butiuc-Keul Anca, Pârvu Marcel

机构信息

Faculty of Biology and Geology, Babeș-Bolyai University, 1, M. Kogălniceanu Street, 400084 Cluj-Napoca, Romania.

Doctoral School of Integrative Biology, Babeș-Bolyai University, 400015 Cluj-Napoca, Romania.

出版信息

Antioxidants (Basel). 2024 Sep 29;13(10):1182. doi: 10.3390/antiox13101182.


DOI:10.3390/antiox13101182
PMID:39456436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11504208/
Abstract

Medicinal plants are a valuable reservoir of novel pharmacologically active compounds. ROS and free radicals are primary contributors to oxidative stress, a condition associated with the onset of degenerative diseases such as cancer, coronary heart disease, and vascular disease. In this study, we used different spectrophotometry methods to demonstrate the antioxidant properties of 6 extracts: ; ; : Arieș red cultivar of , and white variety of ; ; and subsp. . HPLC-MS determined the chemical composition of the extracts. Among the tested extracts, the Arieș red cultivar of stands out as having the best antioxidant activity, probably due to the high content of polyphenols and alliin (12.67 µg/mL and 3565 ng/mL, respectively). The results obtained in this study show that extracts have antioxidant activity, but also free radical scavenging capabilities. Also, their interactions with cytochrome c and hemoglobin can be the basis of future studies to create treatments for oxidative stress-related diseases.

摘要

药用植物是新型药理活性化合物的宝贵来源。活性氧(ROS)和自由基是氧化应激的主要促成因素,氧化应激是一种与癌症、冠心病和血管疾病等退行性疾病的发病相关的状况。在本研究中,我们使用不同的分光光度法来证明6种提取物的抗氧化特性:;;:的阿里什红品种,以及的白色品种;;和亚种。高效液相色谱-质谱联用(HPLC-MS)测定了提取物的化学成分。在测试的提取物中,的阿里什红品种表现出最佳的抗氧化活性,这可能归因于其多酚和蒜氨酸的高含量(分别为12.67μg/mL和3565ng/mL)。本研究获得的结果表明,提取物具有抗氧化活性,同时也具有自由基清除能力。此外,它们与细胞色素c和血红蛋白的相互作用可能成为未来研究开发与氧化应激相关疾病治疗方法的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/3ccc91ec3727/antioxidants-13-01182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/168429ead696/antioxidants-13-01182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/1e8c2e6f8c9d/antioxidants-13-01182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/a144f720eb14/antioxidants-13-01182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/3ccc91ec3727/antioxidants-13-01182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/168429ead696/antioxidants-13-01182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/1e8c2e6f8c9d/antioxidants-13-01182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/a144f720eb14/antioxidants-13-01182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8795/11504208/3ccc91ec3727/antioxidants-13-01182-g004.jpg

相似文献

[1]
Chemical Composition and Antioxidant Activity of Six Extracts Using Protein-Based Biomimetic Methods.

Antioxidants (Basel). 2024-9-29

[2]
Chemical composition, in vitro antioxidant and anti-inflammatory properties of essential oils of four dietary and medicinal plants from Cameroon.

BMC Complement Altern Med. 2016-4-7

[3]
Determination of some polyphenolic compounds from Allium species by HPLC-UV-MS.

Nat Prod Res. 2010-9

[4]
Chemical constituents of three Allium species from Romania.

Molecules. 2012-12-21

[5]
Chemical Composition and Biological Activity of Allium cepa L. and Allium × cornutum (Clementi ex Visiani 1842) Methanolic Extracts.

Molecules. 2017-3-11

[6]
Antioxidant Properties and Structure-Antioxidant Activity Relationship of Species Leaves.

Molecules. 2021-11-26

[7]
Comprehensive metabolomics and antioxidant activity of Allium species viz. Allium semenovii, A. sativum and A. cepa: An important spice.

Food Res Int. 2023-4

[8]
Evaluation of anti-tyrosinase activity of Allium ursinum extracts and their metal complexes.

Acta Sci Pol Technol Aliment. 2018

[9]
Phytochemical Profiles and Antimicrobial Activities of Allium cepa Red cv. and A. sativum Subjected to Different Drying Methods: A Comparative MS-Based Metabolomics.

Molecules. 2017-5-8

[10]
A comparative profile of methanol extracts of Allium cepa and Allium sativum in diabetic neuropathy in mice.

Pharmacognosy Res. 2010-11

引用本文的文献

[1]
Immunomodulatory effect of allium sativum in type 2 diabetes mellitus.

World J Exp Med. 2025-6-20

[2]
Bioactivity-Guided Isolation of Secondary Metabolites from : Antioxidative Antibacterial Activities and Anti-Inflammatory Hypoglycemic Molecular Docking.

Foods. 2024-10-28

本文引用的文献

[1]
Health-promoting properties of bioactive proteins and peptides of garlic (Allium sativum).

Food Chem. 2024-3-1

[2]
Characterization of binding by sulfonylureas with normal or modified human serum albumin using affinity microcolumns prepared by entrapment.

J Chromatogr B Analyt Technol Biomed Life Sci. 2023-7-15

[3]
Phytochemical Characterization and Antimicrobial Activity of Several Extracts.

Molecules. 2023-5-9

[4]
The Effect of Extraction Methods on Phytochemicals and Biological Activities of Green Coffee Beans Extracts.

Plants (Basel). 2023-2-6

[5]
Species: From Optimization of the Extraction Process to Evaluation of Biological Properties.

Antioxidants (Basel). 2022-12-30

[6]
Influences of Different Extraction Techniques and Their Respective Parameters on the Phytochemical Profile and Biological Activities of L. Extracts.

Plants (Basel). 2022-12-24

[7]
Bioactivity and Therapeutic Potential of Kaempferol and Quercetin: New Insights for Plant and Human Health.

Plants (Basel). 2022-10-5

[8]
Antibacterial Potential of Extract Prepared by the Green Extraction Method.

Microorganisms. 2022-7-6

[9]
Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System.

Antioxidants (Basel). 2022-6-26

[10]
Chemical Stability of Ascorbic Acid Integrated into Commercial Products: A Review on Bioactivity and Delivery Technology.

Antioxidants (Basel). 2022-1-13

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索