Amezcua-Guerra Luis M, Velázquez-Espinosa Kelly P, Piña-Soto Lizbeth A, Gutiérrez-Esparza Guadalupe O, Martínez-García Mireya, Brianza-Padilla Malinalli
Department of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Tlapan, Mexico City 14080, Mexico.
Health Care Department, Universidad Autónoma Metropolitana-Xochimilco, Coyoacán, Mexico City 04960, Mexico.
J Clin Med. 2024 Oct 12;13(20):6089. doi: 10.3390/jcm13206089.
A well-established association exists between the development of hypertension and sleep quality. The connection between self-reported sleep quality and the onset of hypertension is particularly significant in populations with metabolic deterioration, such as in Mexico. The Tlalpan 2020 Cohort was analyzed to explore this association. Clinical and anthropometric characteristics, along with the Medical Outcomes Study Sleep Scale (MOS-SS), were compared between participants who developed hypertension and those who did not over a follow-up period of 30.8 months. The potential role of poor sleep quality in the development of hypertension was assessed. Among 1520 participants, 12% developed hypertension. These individuals had higher anthropometric and laboratory values and reported poorer sleep quality. An elevated sleep problems index was associated with a 50% higher relative risk of developing hypertension (OR: 1.5; 95% CI: 1.087 to 2.069). Additionally, self-reported snoring was associated with hypertension onset (36.3 vs. 43.3; = 0.019). Poor sleep quality and respiratory disturbances during sleep increase the risk of developing hypertension. Furthermore, hypertension was associated with snoring, highlighting the importance of early interventions to improve sleep quality.
高血压的发展与睡眠质量之间存在着一种既定的关联。在代谢恶化的人群中，如在墨西哥，自我报告的睡眠质量与高血压发病之间的联系尤为显著。对特拉尔潘2020队列进行了分析，以探究这种关联。在30.8个月的随访期内，比较了发生高血压的参与者和未发生高血压的参与者的临床和人体测量特征，以及医学结局研究睡眠量表（MOS-SS）。评估了睡眠质量差在高血压发展中的潜在作用。在1520名参与者中，12%的人患上了高血压。这些人的人体测量和实验室值较高，且报告的睡眠质量较差。睡眠问题指数升高与患高血压的相对风险高50%相关（比值比：1.5；95%置信区间：1.087至2.069）。此外，自我报告的打鼾与高血压发病相关（36.3对43.3；P = 0.019）。睡眠质量差和睡眠期间的呼吸障碍会增加患高血压的风险。此外，高血压与打鼾相关，这突出了早期干预以改善睡眠质量的重要性。
