Bak Hye Rang, Jang Hye-Jin, Koh Hyun-Min, Ko Nak Gyeong, Cho Young Hye
Department of Family Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Republic of Korea.
Department of Family Medicine, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
J Clin Med. 2024 Oct 14;13(20):6108. doi: 10.3390/jcm13206108.
: This study examined the association between sarcopenic obesity and arterial stiffness using bioelectrical impedance analysis (BIA). : This retrospective cross-sectional study included 20,601 Korean adults from January 2016 to December 2023. Sarcopenia was defined as height-adjusted appendicular skeletal muscle mass [(ASM/height) <5.7 in women and <7.0 in men] using BIA. Obesity was defined by body mass index or waist circumference. Arterial stiffness was assessed by measuring brachial-ankle pulse wave velocity (baPWV). The participants were categorized into four groups: normal, sarcopenia, obesity, and sarcopenic obesity. The baPWV values were compared among the four groups to investigate the association between sarcopenic obesity and arterial stiffness using adjusted multivariate analyses. : The mean baPWV of the sarcopenic obesity group was higher ( < 0.001) than that of the other groups. The odds ratio for having high baPWV (>1800 cm/s) in the sarcopenic obesity group was 2.40 (95% CI, 1.07-5.38) after adjusting for age, sex, exercise, smoking, heavy alcohol consumption, hypertension, and dyslipidemia. : Sarcopenic obesity was independently associated with increased arterial stiffness.
本研究使用生物电阻抗分析（BIA）来检验肌少症性肥胖与动脉僵硬度之间的关联。本项回顾性横断面研究纳入了2016年1月至2023年12月期间的20601名韩国成年人。使用BIA将肌少症定义为身高校正的四肢骨骼肌质量[（ASM/身高）女性<5.7，男性<7.0]。肥胖通过体重指数或腰围来定义。通过测量臂踝脉搏波速度（baPWV）来评估动脉僵硬度。参与者被分为四组：正常组、肌少症组、肥胖组和肌少症性肥胖组。在四组之间比较baPWV值，使用校正后的多变量分析来研究肌少症性肥胖与动脉僵硬度之间的关联。肌少症性肥胖组的平均baPWV高于其他组（<0.001）。在调整年龄、性别、运动、吸烟、大量饮酒、高血压和血脂异常后，肌少症性肥胖组baPWV高（>1800 cm/s）的优势比为2.40（95%CI，1.07 - 5.38）。肌少症性肥胖与动脉僵硬度增加独立相关。
