• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阴部神经阻滞与椎管内麻醉在肛肠外科手术中的效果比较:疗效、安全性和患者结局。

Comparison of Pudendal Nerve Block and Spinal Anesthesia in Proctological Surgeries: Efficacy, Safety, and Patient Outcomes.

机构信息

Department of General Surgery, School of Medicine, Muğla Sıtkı Koçman University, Muğla 48121, Türkiye.

出版信息

Medicina (Kaunas). 2024 Oct 9;60(10):1651. doi: 10.3390/medicina60101651.

DOI:10.3390/medicina60101651
PMID:39459438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11509845/
Abstract

The selection of an appropriate anesthesia method is a critical factor in the surgical treatment of proctological diseases, significantly impacting patient outcomes and comfort. Pudendal nerve block (PNB) and spinal anesthesia (SA) are commonly employed in these surgeries, yet the optimal choice between the two remains debated. This study aims to compare the efficacy and safety of PNB and SA in patients undergoing surgical treatment for various proctological conditions, with a focus on postoperative pain management, functional outcomes, and complication rates. A prospective observational study was conducted on 590 patients who underwent proctological surgery under either PNB (n = 435) or SA (n = 155). Pain levels were assessed using the Visual Analog Scale (VAS), while functional outcomes were measured using the World Health Organization Disability Assessment Schedule (WHODAS 2.0). Statistical analysis was performed to compare the outcomes between the two groups. Patients in the PNB group reported significantly lower postoperative VAS scores compared to those in the SA group, particularly in hemorrhoidectomy and laser hemorrhoidoplasty procedures. The PNB group also demonstrated superior functional outcomes, with lower postoperative WHODAS 2.0 scores and a reduced incidence of urinary retention compared to the SA group. Furthermore, the duration of surgery and hospital stay were significantly shorter for patients in the PNB group. The findings suggest that PNB may offer advantages over SA in proctological surgeries, particularly in terms of pain management, functional recovery, and reduced complication rates. PNB should be considered a viable alternative to SA, particularly in cases where rapid recovery and minimizing complications are priorities. Exceptions to this include specific proctological surgeries, such as those for malignant tumors in the region, complex anal fistulas, proctological conditions arising from inflammatory bowel diseases, and patients on immunosuppressive therapy. Further research is needed to confirm these results and optimize anesthesia selection in this context.

摘要

选择合适的麻醉方法是肛肠疾病外科治疗的关键因素,对患者的预后和舒适度有重要影响。阴部神经阻滞(PNB)和脊髓麻醉(SA)常用于此类手术,但两者之间的最佳选择仍存在争议。本研究旨在比较 PNB 和 SA 在接受各种肛肠疾病手术治疗的患者中的疗效和安全性,重点关注术后疼痛管理、功能结果和并发症发生率。

一项前瞻性观察研究纳入了 590 名接受 PNB(n = 435)或 SA(n = 155)治疗的肛肠疾病手术患者。使用视觉模拟评分(VAS)评估疼痛程度,使用世界卫生组织残疾评估量表(WHODAS 2.0)测量功能结果。采用统计学方法比较两组间的结果。

PNB 组患者术后 VAS 评分明显低于 SA 组,尤其是在痔切除术和激光痔切除术患者中。PNB 组的功能结果也更好,术后 WHODAS 2.0 评分较低,且与 SA 组相比,尿潴留的发生率更低。此外,PNB 组的手术时间和住院时间明显更短。

研究结果表明,PNB 在肛肠手术中可能优于 SA,特别是在疼痛管理、功能恢复和降低并发症发生率方面。PNB 应被视为 SA 的可行替代方案,特别是在快速恢复和尽量减少并发症的情况下。但对于该区域的恶性肿瘤、复杂肛瘘、炎症性肠病引起的肛肠疾病和接受免疫抑制治疗的患者等特定肛肠手术,SA 可能更为适用。需要进一步的研究来证实这些结果,并优化该背景下的麻醉选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a53/11509845/27c37438ec2e/medicina-60-01651-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a53/11509845/6a94701b0a4e/medicina-60-01651-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a53/11509845/27c37438ec2e/medicina-60-01651-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a53/11509845/6a94701b0a4e/medicina-60-01651-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a53/11509845/27c37438ec2e/medicina-60-01651-g002.jpg

相似文献

1
Comparison of Pudendal Nerve Block and Spinal Anesthesia in Proctological Surgeries: Efficacy, Safety, and Patient Outcomes.阴部神经阻滞与椎管内麻醉在肛肠外科手术中的效果比较:疗效、安全性和患者结局。
Medicina (Kaunas). 2024 Oct 9;60(10):1651. doi: 10.3390/medicina60101651.
2
Ultrasound-Guided Pudendal Nerve Block Combined with Propofol Deep Sedation versus Spinal Anesthesia for Hemorrhoidectomy: A Prospective Randomized Study.超声引导阴部神经阻滞联合异丙酚深度镇静与椎管内麻醉用于痔切除术:一项前瞻性随机研究。
Pain Res Manag. 2021 Feb 26;2021:6644262. doi: 10.1155/2021/6644262. eCollection 2021.
3
Pudendal nerve block: a safe, simple and effective approach in surgical proctological patients.阴部神经阻滞:肛肠外科手术患者安全、简单、有效的方法。
Minerva Surg. 2022 Jun;77(3):257-262. doi: 10.23736/S2724-5691.21.08810-9. Epub 2021 Aug 2.
4
Nerve stimulator-guided pudendal nerve block vs general anesthesia for postoperative pain management after anterior and posterior vaginal wall repair: a prospective randomized trial.神经刺激器引导阴部神经阻滞与全身麻醉用于前、后壁阴道修补术后的疼痛管理:一项前瞻性随机试验。
J Clin Anesth. 2016 Nov;34:668-75. doi: 10.1016/j.jclinane.2016.07.024. Epub 2016 Aug 24.
5
Effect of Pudendal Nerve Block on the Prevention of Postoperative Bladder Spasm and Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Holmium Laser Enucleation of the Prostate.阴部神经阻滞对经尿道钬激光前列腺剜除术男性患者术后膀胱痉挛和导尿管相关性膀胱不适的预防作用。
Clin Interv Aging. 2022 Nov 30;17:1729-1738. doi: 10.2147/CIA.S384612. eCollection 2022.
6
Does pudendal nerve block improve perioperative pain following OnabotulinumtoxinA injection for myofascial pelvic pain?阴部神经阻滞能否改善注射A型肉毒毒素治疗盆底肌筋膜疼痛围手术期的疼痛?
Eur J Obstet Gynecol Reprod Biol. 2025 Mar;306:64-68. doi: 10.1016/j.ejogrb.2024.12.055. Epub 2025 Jan 2.
7
Pudendal Nerve Block in Hemorrhoid Surgery: A Systematic Review and Meta-analysis.痔手术中阴部神经阻滞:系统评价和荟萃分析。
Dis Colon Rectum. 2021 May;64(5):617-631. doi: 10.1097/DCR.0000000000001985.
8
The pudendal nerve block for ambulatory urology: What's old is new again. A quality improvement project.门诊泌尿外科的阴部神经阻滞:旧术新用。一项质量改进项目。
J Pediatr Urol. 2020 Oct;16(5):594.e1-594.e7. doi: 10.1016/j.jpurol.2020.07.025. Epub 2020 Jul 24.
9
Ultrasound-Guided Pudendal Nerve Block versus Ultrasound-Guided Dorsal Penile Nerve Block for Pediatric Distal Hypospadias Surgery.超声引导阴部神经阻滞与超声引导阴茎背神经阻滞在小儿远端尿道下裂手术中的比较。
Urol Int. 2023;107(4):370-376. doi: 10.1159/000521718. Epub 2022 Feb 10.
10
The effectiveness of pudendal nerve block versus caudal block anesthesia for hypospadias in children.阴部神经阻滞与骶管阻滞麻醉在小儿尿道下裂中的效果比较。
Anesth Analg. 2013 Dec;117(6):1401-7. doi: 10.1213/ANE.0b013e3182a8ee52.

本文引用的文献

1
Pudendal Nerve Block Analgesia at the Time of Vaginal Surgery: A Randomized, Double-Blinded, Sham-Controlled Trial.阴部神经阻滞镇痛在阴道手术中的应用:一项随机、双盲、假对照试验。
Urogynecology (Phila). 2023 Oct 1;29(10):827-835. doi: 10.1097/SPV.0000000000001351. Epub 2023 Apr 4.
2
Pudendal Nerve Block for Posthemorrhoidectomy Pain: A Prospective, Single-Blinded Randomized Control Trial.痔切除术后疼痛的阴部神经阻滞:一项前瞻性、单盲随机对照试验。
Dis Colon Rectum. 2022 Apr 1;65(4):546-551. doi: 10.1097/DCR.0000000000002293.
3
Local Perianal Anesthetic Infiltration Is Safe and Effective for Anorectal Surgery.
局部肛周麻醉浸润用于肛肠手术安全有效。
Front Surg. 2021 Sep 9;8:730261. doi: 10.3389/fsurg.2021.730261. eCollection 2021.
4
Pudendal nerve block: a safe, simple and effective approach in surgical proctological patients.阴部神经阻滞:肛肠外科手术患者安全、简单、有效的方法。
Minerva Surg. 2022 Jun;77(3):257-262. doi: 10.23736/S2724-5691.21.08810-9. Epub 2021 Aug 2.
5
Intrapartum pudendal nerve block analgesia and risk of postpartum urinary retention: a cohort study.产时阴部神经阻滞镇痛与产后尿潴留风险:一项队列研究。
Int Urogynecol J. 2021 Sep;32(9):2383-2391. doi: 10.1007/s00192-021-04768-0. Epub 2021 Apr 16.
6
Pudendal Nerve Block in Hemorrhoid Surgery: A Systematic Review and Meta-analysis.痔手术中阴部神经阻滞:系统评价和荟萃分析。
Dis Colon Rectum. 2021 May;64(5):617-631. doi: 10.1097/DCR.0000000000001985.
7
Ultrasound-guided pudendal nerve block in patients undergoing open hemorrhoidectomy: a double-blind randomized controlled trial.超声引导阴部神经阻滞在开放式痔切除术患者中的应用:一项双盲随机对照试验。
Int J Colorectal Dis. 2020 Sep;35(9):1741-1747. doi: 10.1007/s00384-020-03630-x. Epub 2020 May 30.
8
Perianal block with ropivacaine as a supplement to anaesthesia in proctological surgery: double-blind randomized placebo-controlled trial (PERCEPT).肛门周围阻滞麻醉联合罗哌卡因在肛肠手术中的应用:一项双盲随机安慰剂对照试验(PERCEPT)。
Br J Surg. 2020 Jul;107(8):960-969. doi: 10.1002/bjs.11520. Epub 2020 Mar 18.
9
How is your proctology patient really doing? Outcome measurement in proctology: development, design and validation study of the Proctoprom.你的肛肠病患者情况如何?肛肠病学的结局测量:Proctoprom 的开发、设计和验证研究。
Tech Coloproctol. 2020 Apr;24(4):291-300. doi: 10.1007/s10151-020-02156-2. Epub 2020 Feb 28.
10
Outpatient management of proctologic disease. Which techniques for local anesthesia? The experience of a single center.直肠疾病的门诊管理。局部麻醉采用哪些技术?单中心经验。
G Chir. 2019 May-Jun;40(3):182-187.