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视神经胶质母细胞瘤伴视交叉受累:病例报告及文献复习。

Optic Nerve Glioblastoma with Optic Chiasm Involvement: A Case Report and a Brief Literature Review.

机构信息

Department of Radiology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia.

Institute of Diagnostic Radiology, Pauls Stradins Clinical University Hospital, 13 Pilsonu Street, LV-1002 Riga, Latvia.

出版信息

Medicina (Kaunas). 2024 Oct 14;60(10):1687. doi: 10.3390/medicina60101687.

Abstract

: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimaging findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment plan for optic nerve glioblastoma results in poor patient survival rates. : a 68-year-old woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight, and partial loss of vision. Using radiological data together with postoperative histopathological and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement was diagnosed. : optic nerve glioblastoma is a rare and aggressive form of cancer that affects the optic nerve, leading to significant vision impairment and potentially life-threatening complications. Treatment options are restricted and difficult because of the location and nature of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a multidisciplinary approach.

摘要

视神经胶质母细胞瘤是一种罕见的病理学。肿瘤可能起源于视交叉、视束或视神经。大多数神经影像学表现是非特异性的。为了明确诊断,需要进行活检。视神经胶质母细胞瘤的治疗计划延迟会导致患者生存率下降。

一名 68 岁女性,无复杂病史,表现为眼球突出、视力恶化和部分视力丧失。结合术后组织病理学和组织化学分析的放射学数据,诊断为 IDH 野生型视神经胶质母细胞瘤,伴有视交叉受累。

视神经胶质母细胞瘤是一种罕见且侵袭性的癌症,影响视神经,导致严重的视力障碍,并可能危及生命。由于病情的位置和性质,治疗选择有限且困难;手术、放疗和化疗经常需要作为多学科治疗的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c5/11509173/59e39a3d8d02/medicina-60-01687-g001.jpg

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