Gardin J M, Kozlowski J, Dabestani A, Murphy M, Kusnick C, Allfie A, Russell D, Henry W L
Am J Cardiol. 1986 Feb 1;57(4):327-32. doi: 10.1016/0002-9149(86)90913-6.
Although Doppler echocardiography is useful in the assessment of left ventricular function at rest, little information is available on the application of this technique during exercise. Consequently, Doppler aortic flow studies were performed in 17 young normal subjects during and after supine bicycle exercise. The purposes of the study were to determine the feasibility of recording Doppler aortic flow velocity with a suprasternal notch transducer during exercise and to assess the changes in normal aortic flow velocity parameters during exercise and early recovery. Each subject exercised until fatigue; mean duration of exercise was 10 minutes. Heart rate increased from a mean of 69 beats/min at control to 159 beats/min at peak exercise. On average, aortic peak flow velocity increased by 45% from control, reaching its maximum at 2 minutes after exercise. Ejection time decreased by 34% during exercise, being shortest at peak exercise. Heart rate, peak flow velocity and ejection time had not returned to normal by 10 minutes after exercise. Aortic flow velocity integral (a relative measure of stroke volume) decreased by 10% at peak exercise (p less than 0.05) compared with control, but had returned to control at 2 minutes after exercise. Despite mild aliasing, increased spectral dispersion, faster heart rates and increased respiratory rate during maximal exercise, aortic flow velocity measurements could be recorded using the suprasternal technique. These baseline Doppler exercise data should be useful in further studies of exercise hemodynamic changes in patients with heart disease.
虽然多普勒超声心动图在评估静息状态下的左心室功能方面很有用,但关于该技术在运动期间的应用,目前可用信息很少。因此,对17名年轻健康受试者在仰卧位自行车运动期间及运动后进行了多普勒主动脉血流研究。本研究的目的是确定在运动期间使用胸骨上切迹换能器记录多普勒主动脉血流速度的可行性,并评估运动期间及早期恢复过程中正常主动脉血流速度参数的变化。每位受试者运动至疲劳;平均运动持续时间为10分钟。心率从对照时的平均69次/分钟增加到运动峰值时的159次/分钟。平均而言,主动脉峰值血流速度较对照时增加了45%,在运动后2分钟达到最大值。射血时间在运动期间减少了34%,在运动峰值时最短。运动后10分钟,心率、峰值血流速度和射血时间尚未恢复正常。与对照相比,运动峰值时主动脉血流速度积分(每搏量的相对测量值)降低了10%(p<0.05),但在运动后2分钟已恢复到对照水平。尽管在最大运动期间存在轻度混叠、频谱离散增加、心率加快和呼吸频率增加,但使用胸骨上技术仍可记录主动脉血流速度测量值。这些多普勒运动基线数据应有助于进一步研究心脏病患者运动时的血流动力学变化。