Qin Yali, Yao Liping, Yuan Ling, Chen Sheng
School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China.
Department of Ultrasound, Shanghai First Maternity and Infant Health Hospital, Shanghai 201204, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Oct 25;41(5):1012-1018. doi: 10.7507/1001-5515.202403033.
Because of the diversity and complexity of clinical indicators, it is difficult to establish a comprehensive and reliable prediction model for induction of labor (IOL) outcomes with existing methods. This study aims to analyze the clinical indicators related to IOL and to develop and evaluate a prediction model based on a small-sample of data. The study population consisted of a total of 90 pregnant women who underwent IOL between February 2023 and January 2024 at the Shanghai First Maternity and Infant Healthcare Hospital, and a total of 52 clinical indicators were recorded. Maximal information coefficient (MIC) was used to select features for clinical indicators to reduce the risk of overfitting caused by high-dimensional features. Then, based on the features selected by MIC, the support vector machine (SVM) model based on small samples was compared and analyzed with the fully connected neural network (FCNN) model based on large samples in deep learning, and the receiver operating characteristic (ROC) curve was given. By calculating the MIC score, the final feature dimension was reduced from 55 to 15, and the area under curve (AUC) of the SVM model was improved from 0.872 before feature selection to 0.923. Model comparison results showed that SVM had better prediction performance than FCNN. This study demonstrates that SVM successfully predicted IOL outcomes, and the MIC feature selection effectively improves the model's generalization ability, making the prediction results more stable. This study provides a reliable method for predicting the outcome of induced labor with potential clinical applications.
由于临床指标的多样性和复杂性,利用现有方法难以建立一个全面且可靠的引产(IOL)结局预测模型。本研究旨在分析与引产相关的临床指标,并基于小样本数据开发和评估一个预测模型。研究对象为2023年2月至2024年1月期间在上海市第一妇婴保健院接受引产的90名孕妇,共记录了52项临床指标。采用最大信息系数(MIC)对临床指标进行特征选择,以降低高维特征导致的过拟合风险。然后,基于MIC选择的特征,将深度学习中基于小样本的支持向量机(SVM)模型与基于大样本的全连接神经网络(FCNN)模型进行比较分析,并给出受试者工作特征(ROC)曲线。通过计算MIC得分,最终特征维度从55维降至15维,SVM模型的曲线下面积(AUC)从特征选择前的0.872提高到0.923。模型比较结果表明,SVM的预测性能优于FCNN。本研究表明,SVM成功预测了引产结局,且MIC特征选择有效提高了模型的泛化能力,使预测结果更稳定。本研究为预测引产结局提供了一种可靠的方法,具有潜在的临床应用价值。