Nguyen Lynhda, Seeber Nikolaus, Baron Jens M, Hammes Stefan, Karsai Syrus, Fischer Tanja C, Imhof Laurence, Kautz Gerd, Sattler Sonja, Deussing Maximilian, Dierckxsens Cathy, Thiem Alexander, Drosos Zacharias, Grosse-Buening Stephan, Ganjuur Nomun, Kampmann Anna-Sophie, May Johanna K, Schneider Stefan W, Kerscher Martina, Herberger Katharina
Laser Department, Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Joint Practice for Dermatology Dres. Peter/Seeber/Altheide, Hamburg, Germany.
J Cosmet Dermatol. 2025 Jan;24(1):e16593. doi: 10.1111/jocd.16593. Epub 2024 Oct 27.
Telangiectasia is a prominent feature of rosacea leading to a high demand for effective treatment. To ensure consistent clinical and scientific evaluations and assess treatment response accurately, standardized assessment tools are necessary for grading the severity of telangiectasia. However, no validated grading scales for this condition are currently available.
To develop and validate a photonumeric scale for assessing the severity of telangiectasia in rosacea patients.
The five-point photonumeric Telangiectasia in Rosacea Severity Assessment (TRoSA) scale was developed for the severity of telangiectasia in rosacea. Sixteen experts participated in the validation process, evaluating 50 images of rosacea patients in two rounds. Interrater and intrarater reliability were analyzed using the intraclass correlation coefficient (ICC) and weighted kappa, respectively.
Interrater reliability was found to be "almost perfect" in both validation rounds (Round 1: ICC 0.847; Round 2: ICC 0.828). The mean weighted kappa indicated "substantial" intrarater reliability between the two rounds with a weighted kappa of 0.719. A bubble plot of the two rounds illustrated a diagonal order, confirming the consistency of the intrarater agreement.
The TRoSA scale demonstrated high interrater and intrarater reliability indicating that it is a consistent and reproducible tool for grading the severity of telangiectasia in rosacea. This scale can standardize clinical assessments, assisting in diagnosis, treatment planning, and evaluation of therapeutic efficacy.
毛细血管扩张是酒渣鼻的一个显著特征，导致对有效治疗的需求很高。为确保一致的临床和科学评估并准确评估治疗反应，需要标准化的评估工具来对毛细血管扩张的严重程度进行分级。然而，目前尚无针对这种情况的经过验证的分级量表。
开发并验证一种用于评估酒渣鼻患者毛细血管扩张严重程度的数字评分量表。
开发了用于评估酒渣鼻患者毛细血管扩张严重程度的五点数字评分量表——酒渣鼻毛细血管扩张严重程度评估（TRoSA）量表。16名专家参与了验证过程，分两轮评估了50张酒渣鼻患者的图像。分别使用组内相关系数（ICC）和加权kappa分析评分者间信度和评分者内信度。
在两轮验证中，评分者间信度均为“几乎完美”（第一轮：ICC为0.847；第二轮：ICC为0.828）。两轮之间的平均加权kappa表明评分者内信度为“实质性”，加权kappa为0.719。两轮的气泡图显示出对角线顺序，证实了评分者内一致性。
TRoSA量表显示出较高的评分者间信度和评分者内信度，表明它是一种用于对酒渣鼻患者毛细血管扩张严重程度进行分级的一致且可重复的工具。该量表可以使临床评估标准化，有助于诊断、治疗计划制定和治疗效果评估。
