Department of Dermatology, Medical Center for Public Health of Puning, Puning City, China.
Dermatology Hospital, Southern Medical University, Guangzhou, China.
J Diabetes. 2024 Oct;16(10):e70022. doi: 10.1111/1753-0407.70022.
Highlights Stratum corneum hydration levels are negatively correlated with HbA1c levels and positively correlated with skin surface pH. Individuals with type 2 diabetes display lower levels of stratum corneum hydration. Because low stratum corneum hydration levels can increase circulating levels of proinflammatory cytokines, which are linked to the pathogenesis of type 2 diabetes, improvement in stratum corneum hydration can be an alternative approach in the management of type 2 diabetes.
要点 角质层水分含量与 HbA1c 水平呈负相关,与皮肤表面 pH 值呈正相关。2 型糖尿病患者的角质层水分含量较低。由于低角质层水分含量会增加促炎细胞因子的循环水平,而这些细胞因子与 2 型糖尿病的发病机制有关,因此改善角质层水分含量可能是 2 型糖尿病治疗的一种替代方法。