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获得性免疫缺陷综合征(艾滋病)中鸟分枝杆菌胞内感染的假性戈谢细胞

Pseudogaucher cells in Mycobacterium avium intracellulare infections in acquired immune deficiency syndrome (AIDS).

作者信息

Solis O G, Belmonte A H, Ramaswamy G, Tchertkoff V

出版信息

Am J Clin Pathol. 1986 Feb;85(2):233-5. doi: 10.1093/ajcp/85.2.233.

DOI:10.1093/ajcp/85.2.233
PMID:3946307
Abstract

This report describes a 28-year-old woman with the acquired immune deficiency syndrome (AIDS) with culture-proven disseminated Mycobacterium avium intracellulare infection. The histopathologic and cytologic features in this case were unique in that these organisms that stained positively with the Ziehl-Neelsen and periodic acid-Schiff (PAS) stains were numerous, present intracellularly within histiocytes, transforming them into pseudogaucher cells. Differential diagnostic criteria for pseudogaucher cells and abnormal macrophage handling of the intracellular organisms in AIDS are discussed.

摘要

本报告描述了一名28岁患有获得性免疫缺陷综合征(艾滋病)的女性,其经培养证实患有播散性鸟分枝杆菌胞内感染。该病例的组织病理学和细胞学特征独特,即这些用齐-尼氏染色法和过碘酸-希夫(PAS)染色呈阳性的微生物数量众多,存在于组织细胞内,将它们转化为假戈谢细胞。文中讨论了艾滋病中假戈谢细胞的鉴别诊断标准以及细胞内微生物的异常巨噬细胞处理情况。

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Pseudogaucher cells in Mycobacterium avium intracellulare infections in acquired immune deficiency syndrome (AIDS).获得性免疫缺陷综合征(艾滋病)中鸟分枝杆菌胞内感染的假性戈谢细胞
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Mycobacterium simiae and Mycobacterium avium-M. intracellulare mixed infection in acquired immune deficiency syndrome.猿猴分枝杆菌与鸟分枝杆菌-胞内分枝杆菌在获得性免疫缺陷综合征中的混合感染
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Can J Infect Dis. 1991 Spring;2(1):19-29. doi: 10.1155/1991/476503.
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Pseudo-Gaucher cells in mycobacterial infection: a report of two cases.分枝杆菌感染中的假性戈谢细胞:两例报告
J Clin Pathol. 2005 Oct;58(10):1113-4. doi: 10.1136/jcp.2004.018176.
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Eur J Pediatr. 1994 Apr;153(4):224-33. doi: 10.1007/BF01954507.
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Screening for lysosomal disorders.溶酶体疾病的筛查。
Eur J Pediatr. 1994;153(7 Suppl 1):S38-43. doi: 10.1007/BF02138776.
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Mycobacterium simiae and Mycobacterium avium-M. intracellulare mixed infection in acquired immune deficiency syndrome.猿猴分枝杆菌与鸟分枝杆菌-胞内分枝杆菌在获得性免疫缺陷综合征中的混合感染
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Immunophenotypic analysis of histiocytes involved in AIDS-associated Mycobacterium scrofulaceum infection: similarities with lepromatous lepra.艾滋病相关瘰疬分枝杆菌感染中组织细胞的免疫表型分析:与瘤型麻风的相似性
Clin Exp Immunol. 1991 Aug;85(2):214-8. doi: 10.1111/j.1365-2249.1991.tb05707.x.