Hill A R
Division of Pulmonary Medicine, State University of New York Health Science Center, Brooklyn, New York.
Can J Infect Dis. 1991 Spring;2(1):19-29. doi: 10.1155/1991/476503.
Tuberculosis (TB) remains uniquely important among acquired immune deficiency syndrome (AIDS)-associated opportunistic infections: it presents the greatest public health hazard worldwide, is the most readily curable, and is largely preventable with existing means. Given the expanding pool of human immunodeficiency virus (HIV) seropositive persons, particularly in developing nations where Mycobacterium tuberculosis remains a leading health problem, one can expect a continued rise in TB cases during the 1990s. Global efforts to eliminate TB are now inextricably entwined with the effectiveness of measures to curtail the HIV epidemic. Mycobacterium avium complex infection, currently an intractable late complication of aids, may increase in clinical importance as success in managing other opportunistic infections and HIV disease itself improves. Understanding of the pathogenesis and management of mycobacterial diseases should increase rapidly given the renewed research spurred on by the advent of HIV.
结核病在获得性免疫缺陷综合征（艾滋病）相关的机会性感染中仍然具有独特的重要性：它在全球范围内构成最大的公共卫生危害，是最容易治愈的疾病，并且很大程度上可以通过现有手段预防。鉴于人类免疫缺陷病毒（HIV）血清阳性人群不断增加，尤其是在结核分枝杆菌仍然是主要健康问题的发展中国家，预计在20世纪90年代结核病病例将持续上升。全球消除结核病的努力现在与遏制艾滋病流行措施的有效性紧密相连。鸟分枝杆菌复合群感染目前是艾滋病难以治疗的晚期并发症，随着其他机会性感染和艾滋病本身管理的成功，其临床重要性可能会增加。鉴于HIV出现后重新激发的研究，对分枝杆菌病发病机制和管理的认识应该会迅速提高。
