AlAteeq Mohammed A, Almaneea Abdallh, Althaqeb Eyad K, Aljarallah Meshal F, Alsaleh Abdulazeez E, Alrasheed Malek A
Family Medicine Department, Ministry of National Guard - Health Affairs, Riyadh, SAU.
Family Medicine, King Abdullah International Medical Research Center, Riyadh, SAU.
Cureus. 2024 Sep 25;16(9):e70160. doi: 10.7759/cureus.70160. eCollection 2024 Sep.
Obesity is an ongoing medical condition that continues to rise on a global scale. Numerous metabolic disorders, such as type 2 diabetes mellitus, hyperlipidemia, and hyperuricemia, are closely associated with obesity. This particular study aims to investigate the occurrence of hyperuricemia and its association with other metabolic factors among children and adolescents aged 6 to 14 years who are overweight or obese residing in Riyadh, Saudi Arabia.
In this research, a cross-sectional, descriptive, and analytical study was carried out on 339 children and adolescents. These participants were selected randomly from a list of patients who had sought medical care for overweight and obesity at the pediatric endocrinology, general pediatrics, and family medicine clinics in King Abdulaziz Medical City (KAMC), located in Riyadh, Saudi Arabia, in the period from January 2020 to January 2022. To gather the necessary data, the electronic medical records of the participating individuals were carefully reviewed, encompassing various relevant variables, including demographic characteristics, anthropometric measurements, serum uric acid levels, lipid profiles, and fasting blood sugar.
Out of the total 339 participants, 48 (14.2%) were identified as overweight, while 291 (85.8%) were classified as obese. The study revealed that the overall prevalence of hyperuricemia among the participants was 54%. There was an increased risk of hyperuricemia associated with male gender and elevated levels of LDL and TG.
The significant prevalence of hyperuricemia among children and adolescents who are overweight or obese is evident. In order to improve control and management of this condition, it is crucial to prioritize the promotion of a healthy lifestyle among these individuals.
肥胖是一种持续存在的医学状况，在全球范围内呈上升趋势。许多代谢紊乱，如2型糖尿病、高脂血症和高尿酸血症，都与肥胖密切相关。本研究旨在调查沙特阿拉伯利雅得6至14岁超重或肥胖儿童及青少年高尿酸血症的发生率及其与其他代谢因素的关联。
本研究对339名儿童和青少年进行了横断面、描述性和分析性研究。这些参与者是从2020年1月至2022年1月期间在沙特阿拉伯利雅得阿卜杜勒阿齐兹国王医疗城（KAMC）的儿科内分泌科、普通儿科和家庭医学诊所因超重和肥胖寻求医疗护理的患者名单中随机选取的。为收集必要数据，仔细审查了参与个体的电子病历，包括各种相关变量，如人口统计学特征、人体测量学指标、血清尿酸水平、血脂谱和空腹血糖。
在339名参与者中，48名（14.2%）被确定为超重，291名（85.8%）被归类为肥胖。研究显示，参与者中高尿酸血症的总体患病率为54%。高尿酸血症风险增加与男性性别以及低密度脂蛋白（LDL）和甘油三酯（TG）水平升高有关。
超重或肥胖的儿童及青少年中高尿酸血症的显著患病率显而易见。为改善对这种状况的控制和管理，在这些个体中优先推广健康生活方式至关重要。
