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肺结核背景下成人斯蒂尔病的诊断与治疗挑战

Diagnostic and Treatment Challenges of Adult-Onset Still's Disease in the Background of Pulmonary Tuberculosis.

作者信息

Kurmi Ajay, Sharma Sandipa, Regmi Japana, Pokhrel Sheekha, Gurung Sanjeela

机构信息

Department of Nephrology, Shahid Dharma Bhakta National Transplant Centre, Bhaktapur, NPL.

Department of Medicine, Shivanagar Primary Health Care Center, Bharatpur, NPL.

出版信息

Cureus. 2024 Sep 26;16(9):e70287. doi: 10.7759/cureus.70287. eCollection 2024 Sep.

DOI:10.7759/cureus.70287
PMID:39463675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11512680/
Abstract

Adult-onset Still's disease is a multisystem inflammatory disease characterized by fever, rashes, arthritis, and sore throat. The occurrence of this disease and pulmonary tuberculosis is infrequent, and more data are needed in the literature regarding both conditions. We present the case of a 48-year-old woman undergoing treatment for sputum-positive pulmonary tuberculosis who presented with features suggestive of adult-onset Still's disease. A detailed evaluation led to the diagnosis of adult-onset still's disease with pulmonary tuberculosis, and the patient was managed accordingly.

摘要

成人斯蒂尔病是一种多系统炎症性疾病，其特征为发热、皮疹、关节炎和咽痛。该疾病与肺结核同时发生的情况并不常见，关于这两种病症的文献资料还需要更多。我们报告一例48岁正在接受痰菌阳性肺结核治疗的女性患者，其表现出提示成人斯蒂尔病的特征。经过详细评估，诊断为成人斯蒂尔病合并肺结核，随后对该患者进行了相应治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e494/11512680/64353b242fce/cureus-0016-00000070287-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e494/11512680/64353b242fce/cureus-0016-00000070287-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e494/11512680/64353b242fce/cureus-0016-00000070287-i01.jpg

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本文引用的文献

1
Adult-Onset Still's Disease (AOSD): Advances in Understanding Pathophysiology, Genetics and Emerging Treatment Options.成人Still 病（AOSD）：对发病机制、遗传学和新兴治疗选择的理解的进展。
Drugs. 2024 Mar;84(3):257-274. doi: 10.1007/s40265-024-01993-x. Epub 2024 Mar 5.
2
Progress in Biological Therapies for Adult-Onset Still's Disease.成人斯蒂尔病生物治疗的进展
Biologics. 2022 Apr 21;16:21-34. doi: 10.2147/BTT.S290329. eCollection 2022.
3
A case of adult-onset Still's disease accompanied with pulmonary tuberculosis successfully treated with colchicine.
一例成人斯蒂尔病合并肺结核患者经秋水仙碱治疗成功
Postepy Dermatol Alergol. 2021 Oct;38(5):912-915. doi: 10.5114/ada.2021.110105. Epub 2021 Nov 5.
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Adult-onset Still's disease in focus: Clinical manifestations, diagnosis, treatment, and unmet needs in the era of targeted therapies.成人Still 病聚焦：临床表现、诊断、治疗和靶向治疗时代的未满足需求。
Semin Arthritis Rheum. 2021 Aug;51(4):858-874. doi: 10.1016/j.semarthrit.2021.06.004. Epub 2021 Jun 13.
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