伴有蛋白异常血症的血管免疫母细胞性淋巴结病中无恶性转化的单克隆高丙种球蛋白血症。
Monoclonal hypergammaglobulinemia without malignant transformation in angioimmunoblastic lymphadenopathy with dysproteinemia.
作者信息
Offit K, Macris N T, Finkbeiner J A
出版信息
Am J Med. 1986 Feb;80(2):292-4. doi: 10.1016/0002-9343(86)90025-2.
A patient with angioimmunoblastic lymphadenopathy with dysproteinemia had a monoclonal IgG hypergammaglobulinemia. In contrast to previous reports, the development of a monoclonal paraprotein in the setting of angioimmunoblastic lymphadenopathy with dysproteinemia did not herald a transformation to malignancy. The patient improved clinically and the monoclonal gammopathy disappeared when the patient was treated with prednisone. The relationship of these findings to current concepts regarding the cause of angioimmunoblastic lymphadenopathy with dysproteinemia is discussed.
一名患有血管免疫母细胞性淋巴结病伴蛋白异常血症的患者出现单克隆IgG高丙种球蛋白血症。与既往报道不同的是，在血管免疫母细胞性淋巴结病伴蛋白异常血症情况下出现单克隆副蛋白并不预示着向恶性肿瘤转变。该患者经泼尼松治疗后临床症状改善，单克隆丙种球蛋白病消失。本文讨论了这些发现与目前关于血管免疫母细胞性淋巴结病伴蛋白异常血症病因概念的关系。
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