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紫光透过眼镜及其对近视儿童的影响:一项系统评价和荟萃分析。

Violet light transmission through eyeglasses and its effects on myopic children: A systematic review and meta-analysis.

作者信息

Ullah Saif, Umer Muhammad F, Chandran Suriyakala P

机构信息

Department of Health Sciences, Lincoln University College, Wisma Lincoln, Petaling Jaya, Selangor Darul Ehsan, Malaysia.

Department of Preventive Dental Sciences, College of Dentistry, King Faisal University, Hofuf, Al-Ahsa, Saudi Arabia.

出版信息

Saudi J Ophthalmol. 2024 Sep 27;38(3):235-242. doi: 10.4103/sjopt.sjopt_146_24. eCollection 2024 Jul-Sep.

DOI:10.4103/sjopt.sjopt_146_24
PMID:39465017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11503971/
Abstract

PURPOSE

Myopia is a refractive error that impairs visual function and leads to visual blurring. This study aims to investigate the effect of violet light (VL) on controlling myopia, specifically in terms of axial length (AL), spherical equivalent refraction (SER), and visual acuity (VA).

METHODS

A systematic review was conducted to compare VL and single-vision spectacles (SVSs) for treating childhood myopia. The search terms used were "Myopia" and "Violet Light." Extensive searches were carried out in the PubMed, Embase, and Cochrane databases. The mean differences were evaluated. The effects of the therapy were examined. Publication bias was assessed with a funnel plot and further investigated through sensitivity analysis. Meta-analysis was performed using Bayesian statistics with Jeffery's Amazing Statistical Package.

RESULTS

The meta-analysis included 126 myopic children: 64 in the VL group and 62 in the SVS group. The pooled effect size for AL shortening was evaluated as 0.659 ± 0.184, with a 95% credible interval of 0.299-1.023. The pooled effect size for SER decrease was estimated as 0.669 ± 0.188, with a 95% credible interval of 0.303-1.036. Likewise, for VA in Log-MAR, after intervention (VL and SVS), the values were 0.082 ± 0.171 with a credible interval of 0.262-0.423. Publication bias was assessed with a funnel plot, which revealed no bias. Impact sizes for the fixed effect model were determined due to the similarity in study population, geography, type of intervention, and study design.

CONCLUSION

VL transmission glasses play a significant role in controlling myopia among children, resulting in axial shortening, reduction of SER, and improvement in VA. However, further investigation is required to examine the long-term rebound effect.

摘要

目的

近视是一种损害视觉功能并导致视力模糊的屈光不正。本研究旨在探讨紫光(VL)对控制近视的作用,特别是在眼轴长度(AL)、等效球镜度(SER)和视力(VA)方面。

方法

进行了一项系统评价,比较VL与单焦点眼镜(SVS)治疗儿童近视的效果。使用的检索词为“Myopia”和“Violet Light”。在PubMed、Embase和Cochrane数据库中进行了广泛检索。评估了平均差异,检查了治疗效果。用漏斗图评估发表偏倚,并通过敏感性分析进一步研究。使用Jeffery's Amazing Statistical Package进行贝叶斯统计的荟萃分析。

结果

荟萃分析纳入了126名近视儿童:VL组64名,SVS组62名。AL缩短的合并效应量评估为0.659±0.184,95%可信区间为0.299 - 1.023。SER降低的合并效应量估计为0.669±0.188,95%可信区间为0.303 - 1.036。同样,对于干预后(VL和SVS)的Log-MAR视力,值为0.082±0.171,可信区间为0.262 - 0.423。用漏斗图评估发表偏倚,结果显示无偏倚。由于研究人群、地理位置、干预类型和研究设计的相似性,确定了固定效应模型的效应量。

结论

VL透射眼镜在控制儿童近视方面发挥着重要作用,可导致眼轴缩短、SER降低和视力改善。然而,需要进一步研究来检查长期反弹效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/01abfee23175/SJO-38-235-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/a963dc5c9e5f/SJO-38-235-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/ac624d4877fc/SJO-38-235-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/a45ad101ae6a/SJO-38-235-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/d0c291b086d9/SJO-38-235-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/01abfee23175/SJO-38-235-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/a963dc5c9e5f/SJO-38-235-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/ac624d4877fc/SJO-38-235-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/a45ad101ae6a/SJO-38-235-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/d0c291b086d9/SJO-38-235-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4d/11503971/01abfee23175/SJO-38-235-g005.jpg

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本文引用的文献

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Short-Term Exposure to Violet Light Emitted from Eyeglass Frames in Myopic Children: A Randomized Pilot Clinical Trial.近视儿童短期暴露于眼镜框发出的紫光:一项随机试点临床试验。
J Clin Med. 2022 Oct 11;11(20):6000. doi: 10.3390/jcm11206000.
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Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs.脉络膜血流灌注减少诱导豚鼠近视。
Invest Ophthalmol Vis Sci. 2021 Dec 1;62(15):30. doi: 10.1167/iovs.62.15.30.
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Effect of Violet Light-Transmitting Eyeglasses on Axial Elongation in Myopic Children: A Randomized Controlled Trial.
透紫光眼镜对近视儿童眼轴长度的影响:一项随机对照试验
J Clin Med. 2021 Nov 22;10(22):5462. doi: 10.3390/jcm10225462.
4
Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice.紫光通过神经视蛋白(OPN5)抑制小鼠的近视。
Proc Natl Acad Sci U S A. 2021 Jun 1;118(22). doi: 10.1073/pnas.2018840118.
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IMI Pathologic Myopia.病理性近视
Invest Ophthalmol Vis Sci. 2021 Apr 28;62(5):5. doi: 10.1167/iovs.62.5.5.
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The influence of the choroid on the onset and development of myopia: from perspectives of choroidal thickness and blood flow.脉络膜对近视发生发展的影响:从脉络膜厚度和血流的角度。
Acta Ophthalmol. 2021 Nov;99(7):730-738. doi: 10.1111/aos.14773. Epub 2021 Feb 7.
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Axial length shortening in a myopic child with anisometropic amblyopia after wearing violet light-transmitting eyeglasses for 2 years.一名患有屈光参差性弱视的近视儿童佩戴透紫光眼镜2年后眼轴长度缩短。
Am J Ophthalmol Case Rep. 2020 Dec 11;20:101002. doi: 10.1016/j.ajoc.2020.101002. eCollection 2020 Dec.
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