Aldamri Aljawhara, AlKhaldi Saleh A, Alshuhayb Bayan S, Almutairi Reem T
Department of Ophthalmology, King Saud Medical City, Riyadh, Saudi Arabia.
Research Center, King Saud Medical City, Riyadh, Saudi Arabia.
Saudi J Ophthalmol. 2024 Feb 22;38(3):275-279. doi: 10.4103/sjopt.sjopt_222_23. eCollection 2024 Jul-Sep.
The purpose of this study was to explore the side effects of using cycloplegic eye drops at ophthalmology clinics at King Saud Medical City (KSMC) in Riyadh, Saudi Arabia. Moreover, to have an insight into physicians' attitude towards the management of these side effects.
A retrospective cross-sectional study where medical records of pediatric patients who attended ophthalmology clinics at KSMC. Subjects were selected after reviewing their files and based on their reaction to the ocular drops. In addition, the response of ophthalmologists was obtained through a questionnaire distributed through electronic channels.
A total of 111 patients' medical records were included in this study. The most reported cycloplegic agents that caused side effects were cyclopentolate 1%, tropicamide 1%, and phenylephrine 2.5%. Fifty-three percentage of physicians reported that changing their way of administering cycloplegic drops in practice plays a role in reducing some side effects. The most reported side effects of using cycloplegic eye drops were facial flushing 68%, followed by fever 46%, and irritability 38% of cases. Few children who experienced side effects needed medical intervention.
Side effects caused by cycloplegic agents are usually mild and rarely severe. There are some systemic side effects such as hallucinations, psychosis, or seizures. Proper parental counseling before administering cycloplegic agents and proper clinical management in case of severe side effects is crucial. Prophylactic measures to reduce the incidence of these side effects are advisable.
本研究的目的是探讨在沙特阿拉伯利雅得的国王沙特医疗城（KSMC）眼科诊所使用睫状肌麻痹眼药水的副作用。此外，深入了解医生对这些副作用管理的态度。
一项回顾性横断面研究，研究对象为在KSMC眼科诊所就诊的儿科患者的病历。在查阅他们的档案并根据他们对眼药水的反应进行选择。此外，通过电子渠道分发问卷来获取眼科医生的答复。
本研究共纳入111例患者的病历。报告最多的引起副作用的睫状肌麻痹剂是1%的环喷托酯、1%的托吡卡胺和2.5%的去氧肾上腺素。53%的医生报告说，在实际操作中改变他们使用睫状肌麻痹眼药水的方式对减少一些副作用有作用。使用睫状肌麻痹眼药水报告最多的副作用是面部潮红（68%），其次是发热（46%）和易怒（38%）。少数出现副作用的儿童需要医疗干预。
睫状肌麻痹剂引起的副作用通常较轻，很少严重。存在一些全身性副作用，如幻觉、精神病或癫痫发作。在使用睫状肌麻痹剂之前对家长进行适当的咨询以及在出现严重副作用时进行适当的临床管理至关重要。建议采取预防措施以降低这些副作用的发生率。
