Lipshitz J, Ahokas R A, Reynolds S L, Anderson G D
Am J Obstet Gynecol. 1986 Feb;154(2):314-7. doi: 10.1016/0002-9378(86)90663-0.
To assess whether the maternal-fetal balance could be altered in favor of the fetus during malnutrition by increasing uteroplacental blood flow, 0.5 mg of hexoprenaline per day was added to the diet of one group of diet-restricted rats, while another group served as controls. The radionuclide-labeled microsphere method was used to determine blood flow to the maternal placentas and other organs. Maternal carcass weight but not fetal or placental weights were increased in the hexoprenaline-fed rats. Blood flow to the ileum, jejunum, hepatic artery, kidneys, and placentas was significantly greater in the hexoprenaline group compared with those rats fed the restricted diet alone. Although the placental blood flow was increased in the hexoprenaline-fed rats, the supply of nutrients remained restricted, and in the mother the inherent maternal-fetal balance was maintained by an increase in the blood flow to the liver and small intestine.
为了评估在营养不良期间，增加子宫胎盘血流量是否能改变母胎平衡从而有利于胎儿，一组饮食受限的大鼠每天的饮食中添加0.5毫克的己丙肾上腺素，另一组作为对照。采用放射性核素标记微球法测定母体胎盘和其他器官的血流量。己丙肾上腺素喂养的大鼠母体胴体重量增加，但胎儿或胎盘重量未增加。与仅喂食受限饮食的大鼠相比，己丙肾上腺素组回肠、空肠、肝动脉、肾脏和胎盘的血流量显著增加。虽然己丙肾上腺素喂养的大鼠胎盘血流量增加，但营养供应仍然受限，在母体中，母胎平衡是通过肝脏和小肠血流量的增加来维持的。
