Department of Second Clinical Medical College, Anhui University of Chinese Medicine, Hefei, Anhui Province, China.
Department of Orthopaedics, Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, China.
Medicine (Baltimore). 2024 Oct 4;103(40):e40000. doi: 10.1097/MD.0000000000040000.
Apoptosis, a form of programmed cell death, plays a significant role in osteoarthritis; however, bibliometric studies in this field remain scarce. Bibliometrics provides a visual representation of research outcomes and trends, guiding future investigations.
Journal data from January 1, 2013, to December 31, 2023, in this field were obtained from the Web of Science (WOS) core database. Analysis was conducted using VOSviewer and CiteSpace.
Analysis revealed that over the past decade, 794 articles were published in 299 journals by 4447 authors from 49 countries and 877 institutions. The top contributors were China, the United States, and the United Kingdom. Zhuang Chao emerged as the most prolific author, and "osteoarthritis and cartilage" ranked as the most frequently cited journal. Keyword clustering focused on mechanisms, inflammation, and cartilage. The most-cited article was "chondrocyte apoptosis in the pathogenesis of osteoarthritis" in the "International Journal of Molecular Sciences." Burst word analysis highlighted extracellular matrix, circular RNA, micro RNA, indicating current research hotspots.
Utilizing bibliometrics and visual analysis, we explored the hotspots and trends in the field of chondrocyte apoptosis in osteoarthritis. Extracellular matrix, Circular RNA, Micro RNA, among others, are likely to become future research focal points and frontiers.
细胞凋亡是一种程序性细胞死亡形式，在骨关节炎中起着重要作用；然而，该领域的文献计量学研究仍然很少。文献计量学提供了研究成果和趋势的可视化表示，指导未来的研究。
本研究从 Web of Science（WOS）核心数据库中获取了 2013 年 1 月 1 日至 2023 年 12 月 31 日期间该领域的期刊数据。使用 VOSviewer 和 CiteSpace 进行分析。
分析显示，在过去十年中，来自 49 个国家和 877 个机构的 4447 名作者在 299 种期刊上发表了 794 篇文章。排名前三的国家是中国、美国和英国。庄超是最有影响力的作者，而“骨关节炎与软骨”是被引用最多的期刊。关键词聚类集中在机制、炎症和软骨上。被引用最多的文章是“骨关节炎发病机制中的软骨细胞凋亡”，发表在《国际分子科学杂志》上。突发词分析突出了细胞外基质、环状 RNA、微小 RNA，表明了当前的研究热点。
本研究利用文献计量学和可视化分析探讨了骨关节炎中软骨细胞凋亡领域的热点和趋势。细胞外基质、环状 RNA、微小 RNA 等可能成为未来的研究重点和前沿。
