Pôle Femme Mère Nouveau-né, Universitaire de Lille, CHU Lille, Lille, France.
EA 2694: Epidémiologie et qualité des soins, Universitaire de Lille, Lille, France.
Hum Vaccin Immunother. 2024 Dec 31;20(1):2132799. doi: 10.1080/21645515.2022.2132799. Epub 2024 Oct 28.
In 2016, only 7% of French women had received an influenza vaccination during their pregnancy. In this vaccine-averse country, the possibility of reaching the rates of 50% observed in other countries remains unknown. To measure the rate of influenza vaccination in a French university maternity. To study its evolution and determinants over the last 5 years. Single-center observational study of all women who gave birth during March 2020 in this maternity. Comparison with rates observed in 2015 in the same conditions. Of the 337 women included in the study, 202 received a vaccination during pregnancy (59.9%). After logistic regression, the factors significantly associated with achieving vaccination were the offer of vaccination during pregnancy, odds ratio (ORa) 26.2 [7.0; 98.2]; previous vaccination, ORa 20.3 [9.6; 42.6]; high education level, ORa 2.9 [1.3; 6.2]; delivery of a CERFA government reimbursement form, ORa 2.5 [1.3; 4.8]; a vaccination offer made by a general practitioner, ORa 2.1 [1.0; 4.4] and not by a hospital midwife, ORa 0.3 [0.1; 0.6]. The rate of vaccination increased from 35% to 59.9% between 2015 and 2020 ( < .001), with a significant increase in the offer of vaccination during pregnancy (+14.6%) - especially by a general practitioner (+17.2%) - and in the rate of women with earlier vaccination (+13.6%). In France, vaccination rates above 50% are possible at a center level. A proposal of vaccination during pregnancy - especially by the general practitioner - seems to be a determining factor in this development.
2016 年，只有 7%的法国孕妇接种了流感疫苗。在这个对疫苗持反对态度的国家，达到其他国家 50%的接种率的可能性尚不清楚。评估法国某大学妇产医院孕妇流感疫苗接种率。研究过去 5 年该接种率的变化及其决定因素。这是一项对该妇产医院 2020 年 3 月所有分娩妇女的单中心观察性研究。将该研究与同期（2015 年）相同条件下的接种率进行比较。在纳入研究的 337 名妇女中，有 202 名在孕期接种了疫苗（59.9%）。经过逻辑回归分析，与实现接种相关的因素有孕期提供疫苗接种，比值比（ORa）为 26.2 [7.0；98.2]；既往接种过疫苗，ORa 为 20.3 [9.6；42.6]；高学历，ORa 为 2.9 [1.3；6.2]；收到政府报销表 CERFA，ORa 为 2.5 [1.3；4.8]；由全科医生提供疫苗接种，ORa 为 2.1 [1.0；4.4]，而非医院助产士，ORa 为 0.3 [0.1；0.6]。2015 年至 2020 年期间，疫苗接种率从 35%增加到 59.9%（ < .001），孕期疫苗接种率显著增加（+14.6%）-特别是由全科医生（+17.2%）-以及既往接种疫苗的女性比例增加（+13.6%）。在法国，在中心层面达到 50%以上的疫苗接种率是可能的。孕期接种疫苗的建议-尤其是由全科医生提供-似乎是这一发展的决定性因素。
