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与第三磨牙相关的第二磨牙外吸收的预测模型

A Prediction Model for External Root Resorption of the Second Molars Associated With Third Molars.

作者信息

Kou Zhengwei, Zhang Wuyang, Li Chen, Zhang Yu, Song Zijian, Zou Yuzhen, Wang Haijing, Liu Zhenghua, Huerman Bahetibieke, Deng Tiange, Hu Kaijin, Xue Yang, Ji Ping

机构信息

Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, College of Stomatology, Chongqing Medical University, Chongqing, China; People's Hospital of Shenzhen Baoan District, The Second Affiliated Hospital of Shenzhen University, Shenzhen, China.

Department of Oral and Maxillofacial Surgery, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases & Shaanxi Clinical Research Center for Oral Diseases, School of Stomatology, The Fourth Military Medical University, Xi'an, China.

出版信息

Int Dent J. 2025 Feb;75(1):195-205. doi: 10.1016/j.identj.2024.09.031. Epub 2024 Oct 29.

Abstract

OBJECTIVES

The aim of this study is to investigate risk factors for external root resorption (ERR) of second molars (M2) associated with impacted third molars (M3), and to develop a prediction model that can offer dentists a reliable and efficient tool for predicting the likelihood of ERR.

METHODS

A total of 798 patients with 2156 impacted third molars were collected from three centres between 1 December 2018 and 15 December 2018. ERR was identified by cone beam computed tomography examinations. The effects of different risk factors on the presence/absence of ERR and its severity were analysed using Chi-square or Fisher test. Multivariate logistic regressive analysis with stepwise variable selection methods was performed to identify factors which were significant predictors for ERR and its severity. Subsequently, a prediction model was developed, and the model performance was validated internally and externally.

RESULTS

The overall incidence of ERR of second molars was 16.05%. The prediction model was established using six factors including position (upper/lower jaw), impact type, impact depth (PG: A-B-C), contact position, root number of M3, and age. In terms of internal validation, the prediction model demonstrated satisfactory performance, achieving an area under curve of 0.961 and a prediction accuracy of 0.907. As for external validation, the area under curve remained high at 0.953, with a prediction accuracy of 0.892.

CONCLUSION

A risk prediction model for ERR was established in the present study. Position (upper or lower jaw), impact type, impact depth (PG: A-B-C), contact position, root number of M3, and age were identified as influencing variables which were significant predictors in the development of this predictive model. The prediction model showed great discrimination and calibration.

CLINICAL RELEVANCE

This prediction model has the potential to aid dentists and patients in making clinical decisions regarding the necessity of M3 extraction.

摘要

目的

本研究旨在调查与阻生第三磨牙(M3)相关的第二磨牙(M2)牙根外吸收(ERR)的危险因素,并开发一种预测模型,为牙医提供一种可靠且高效的工具来预测ERR的可能性。

方法

2018年12月1日至2018年12月15日期间,从三个中心收集了798例有2156颗阻生第三磨牙的患者。通过锥形束计算机断层扫描检查确定ERR。使用卡方检验或Fisher检验分析不同危险因素对ERR存在与否及其严重程度的影响。采用逐步变量选择方法进行多因素逻辑回归分析,以确定ERR及其严重程度的显著预测因素。随后,开发了一个预测模型,并在内部和外部对模型性能进行了验证。

结果

第二磨牙ERR的总体发生率为16.05%。使用包括位置(上颌/下颌)、阻生类型、阻生深度(PG:A - B - C)、接触位置、M3的牙根数量和年龄在内的六个因素建立了预测模型。在内部验证方面,预测模型表现出令人满意的性能,曲线下面积为0.961,预测准确率为0.907。在外部验证中,曲线下面积保持在较高水平,为0.953,预测准确率为0.892。

结论

本研究建立了ERR的风险预测模型。位置(上颌或下颌)、阻生类型、阻生深度(PG:A - B - C)、接触位置、M3的牙根数量和年龄被确定为影响变量,是该预测模型开发中的显著预测因素。该预测模型显示出良好的区分度和校准度。

临床意义

该预测模型有可能帮助牙医和患者做出关于拔除M3必要性的临床决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b38/11806329/b52988cda0d4/gr1.jpg

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