低碳水化合物膳食评分（LCDS）与心血管危险因素的关系：来自设拉子心脏研究（SHS）的结果。

The association between low carbohydrate dietary score (LCDS) and cardiovascular risk factors: results from the Shiraz Heart Study (SHS).

机构信息

Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

College of Life Sciences, Birmingham City University, Westbourne Road, Edgbaston, B15 3TN, Birmingham, UK.

出版信息

BMC Public Health. 2024 Oct 29;24(1):2997. doi: 10.1186/s12889-024-20106-7.

DOI:10.1186/s12889-024-20106-7

PMID:39472889

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11523835/

Abstract

BACKGROUND

Cardiovascular disease (CVD) is a major cause of death and recent studies have highlighted the potential role of dietary carbohydrate indices in cardiovascular health. Given the controversial results in this field, the aim of this study was to investigate the association between low carbohydrate dietary score (LCDS) and CVD risk factors in a population of Iranian adults.

METHODS

This cross-sectional study was conducted within the framework of the Shiraz Heart Study (SHS) including 1982 adults. The validated 168 items food frequency questionnaire (FFQ) was used to assess participants' dietary intakes. To investigate the association between LCDS and cardiometabolic risk factors, logistic regression, was conducted.

RESULTS

During 5 years of follow-up, a total of 1982 adults, with a mean age of 53.07 ± 8.38 years, were included to the analysis. The adjusted model based on known confounding factors (age, sex, smoking, physical activity, energy intake and body mass index) revealed a significant decrease in a body shape index (ABSI) (OR = 0.70, 95% CI= (0.50 to 0.98), P = 0.038) comparing highest LCDS tertile vs. the reference. In contrast, risk of hypertension (HTN), body mass index (BMI), waist-hip ratio (WHR), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), atherogenic index of plasma (AIP), and fasting blood sugar (FBS) were not significantly associated with LCDS.

CONCLUSION

Current findings suggest that adherence to a low carbohydrate diet reduces ABSI, a main indicator of central obesity.

摘要

背景

心血管疾病（CVD）是死亡的主要原因，最近的研究强调了饮食碳水化合物指数在心血管健康中的潜在作用。鉴于该领域存在争议的结果，本研究旨在调查伊朗成年人中低碳水化合物饮食评分（LCDS）与 CVD 危险因素之间的关系。

方法

这项横断面研究是在 Shiraz Heart Study（SHS）的框架内进行的，包括 1982 名成年人。使用经过验证的 168 项食物频率问卷（FFQ）来评估参与者的饮食摄入量。为了研究 LCDS 与心血管代谢危险因素之间的关系，进行了逻辑回归分析。

结果

在 5 年的随访期间，共纳入了 1982 名年龄为 53.07±8.38 岁的成年人进行分析。基于已知混杂因素（年龄、性别、吸烟、体力活动、能量摄入和体重指数）的调整模型显示，身体形态指数（ABSI）显著降低（OR=0.70，95%CI=（0.50 至 0.98），P=0.038），与最高 LCDS 三分位相比。相比之下，高血压（HTN）、体重指数（BMI）、腰臀比（WHR）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-c）、高密度脂蛋白胆固醇（HDL-c）、血浆致动脉粥样硬化指数（AIP）和空腹血糖（FBS）与 LCDS 无显著相关性。