Department of Cardiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan.
Department of Internal Medicine, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Japan; Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan.
Clin Nutr ESPEN. 2021 Dec;46:251-258. doi: 10.1016/j.clnesp.2021.10.001. Epub 2021 Oct 8.
A body shape index (ABSI) is a novel anthropometric measure calculated using waist circumference (WC), body mass index (BMI), and body height. This study investigated the usefulness of ABSI to identify individuals with metabolic syndrome (MetS) and increased arterial stiffness in the middle-aged population.
Middle-aged workers who underwent periodic health check-ups and who were without previous cardiovascular events were enrolled (n = 10,182). In addition to ABSI, visceral fat area (VFA) was evaluated using computed tomography. Obesity and MetS were diagnosed on the basis of WC, VFA, and ABSI. Arterial stiffness was examined by measuring the cardio-ankle vascular index (CAVI).
ABSI was significantly associated with CAVI in multivariable regression analysis. Logistic regression analysis revealed that ABSI was independently associated with the presence of MetS diagnosed on the basis of WC or VFA after adjustment for potential confounders, including BMI. Subjects with MetS diagnosed on the basis of each obesity index showed higher CAVI values than those without. Among subjects with MetS diagnosed on the basis of WC or VFA, those with MetS who met the definition of ABSI obesity showed significantly higher CAVI than those who did not. The other logistic regression analysis demonstrated that CAVI was independently associated with MetS defined on the basis of ABSI.
ABSI was significantly associated with CAVI and the presence of MetS in the middle-aged population and helped to discriminate individuals with MetS and increased CAVI. ABSI could serve to identify individuals with MetS and increased arterial stiffness.
体脂指数（ABSI）是一种新的人体测量指标，通过腰围（WC）、体重指数（BMI）和身高计算得出。本研究旨在探讨 ABSI 在中年人群中识别代谢综合征（MetS）和动脉僵硬度增加个体的有用性。
本研究纳入了进行定期健康检查且无既往心血管事件的中年工作者（n=10182）。除了 ABSI，还使用计算机断层扫描评估内脏脂肪面积（VFA）。根据 WC、VFA 和 ABSI 诊断肥胖和 MetS。通过测量心踝血管指数（CAVI）来检查动脉僵硬度。
多变量回归分析显示，ABSI 与 CAVI 显著相关。Logistic 回归分析显示，在调整 BMI 等潜在混杂因素后，ABSI 与基于 WC 或 VFA 诊断的 MetS 独立相关。基于每个肥胖指数诊断为 MetS 的受试者的 CAVI 值均高于无 MetS 者。在基于 WC 或 VFA 诊断为 MetS 的受试者中，符合 ABSI 肥胖定义的 MetS 患者的 CAVI 值显著高于不符合者。另一个 logistic 回归分析表明，CAVI 与基于 ABSI 定义的 MetS 独立相关。
ABSI 与中年人群的 CAVI 和 MetS 显著相关，并有助于区分 MetS 患者和 CAVI 升高的患者。ABSI 可用于识别 MetS 患者和动脉僵硬度增加的患者。
