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结直肠癌中的炎症和营养标志物:对预后和治疗的意义。

Inflammatory and nutritional markers in colorectal cancer: Implications for prognosis and treatment.

作者信息

Tez Mesut

机构信息

Department of Surgery, University of Health Sciences, Ankara City Hospital, Ankara 06800, Türkiye.

出版信息

World J Clin Oncol. 2024 Oct 24;15(10):1264-1268. doi: 10.5306/wjco.v15.i10.1264.

Abstract

The prognosis of colorectal cancer (CRC) patients with peritoneal metastasis remains poor despite advancements in detection and treatment. Preoperative inflammatory and nutritional markers have emerged as significant predictors of prognosis in CRC, potentially guiding treatment decisions and improving patient outcomes. This editorial explores the prognostic value of markers such as the neutrophil-to-lymphocyte ratio, hemoglobin, and serum albumin levels. By integrating these markers into prognostic models, clinicians can better stratify patients, personalize treatment strategies, and ultimately enhance clinical outcomes. This review highlights the importance of these markers in providing a comprehensive assessment of patient condition and underscores the need for further research to validate their clinical utility and uncover underlying mechanisms.

摘要

尽管在检测和治疗方面取得了进展,但结直肠癌(CRC)伴腹膜转移患者的预后仍然很差。术前炎症和营养标志物已成为CRC预后的重要预测指标,可能指导治疗决策并改善患者预后。这篇社论探讨了中性粒细胞与淋巴细胞比值、血红蛋白和血清白蛋白水平等标志物的预后价值。通过将这些标志物纳入预后模型,临床医生可以更好地对患者进行分层,个性化治疗策略,并最终提高临床疗效。这篇综述强调了这些标志物在全面评估患者病情方面的重要性,并强调需要进一步研究以验证其临床效用并揭示潜在机制。

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