Zhao Yun, Bie Yu-Kun, Zhang Guang-Ya, Feng Yi-Bin, Wang Feng
Department of Hepatobiliary Surgery, Ankang Central Hospital, Ankang 725000, Shaanxi Province, China.
World J Gastrointest Oncol. 2024 Oct 15;16(10):4264-4273. doi: 10.4251/wjgo.v16.i10.4264.
Rare liver tumors (RLTs) have an extremely low likelihood of forming, and some have been recorded only in isolated cases. The lack of normal clinical symptoms in RLTs makes preoperative diagnosis extremely challenging, which results in frequent misinterpretation. The present case report helps enhance our ability to recognize and treat uncommon liver tumor disorders.
We describe four distinct examples of rare liver tumor diseases. These cases were all true cases with no conventional clinical signs or imaging findings. In all patients, hepatic occupancy was discovered on physical examination, which raised the preoperative suspicion of hepatic cancer. All tumors were surgically removed, and postoperative histology and immunohistochemistry were performed to confirm the diagnosis. The first patient had primary hepatic fibrosarcoma. The second case involved a primary hepatic neuroendocrine tumors. These two patients had malignant liver tumors, and both had extremely satisfactory surgical outcomes. The third case involved focal hepatic steatosis, and the fourth case involved a single necrotic nodule in the liver. These two patients had benign liver tumors, but they had already undergone surgery and did not require any postoperative care.
The number of patients with RLTs is small, and the clinical and imaging results are vague. Preoperative diagnosis is challenging, and patients are sometimes mistakenly diagnosed with liver cancer, which leads to unnecessary surgical therapy in certain individuals.
罕见肝肿瘤（RLTs）形成的可能性极低，有些仅在个别病例中被记录。RLTs缺乏正常临床症状，这使得术前诊断极具挑战性，常导致误诊。本病例报告有助于提高我们识别和治疗罕见肝肿瘤疾病的能力。
我们描述了四个罕见肝肿瘤疾病的不同实例。这些病例均为真实病例，无传统临床体征或影像学表现。所有患者在体格检查时均发现肝脏占位，这增加了术前对肝癌的怀疑。所有肿瘤均通过手术切除，并进行术后组织学和免疫组化检查以确诊。第一例患者患有原发性肝纤维肉瘤。第二例涉及原发性肝神经内分泌肿瘤。这两名患者患有恶性肝肿瘤，且手术效果都非常令人满意。第三例涉及局灶性肝脂肪变性，第四例涉及肝脏单个坏死结节。这两名患者患有良性肝肿瘤，但他们已经接受了手术，无需任何术后护理。
RLTs患者数量较少，临床和影像学结果不明确。术前诊断具有挑战性，患者有时会被误诊为肝癌，这导致某些个体接受了不必要的手术治疗。
