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多次玻璃体视网膜干预后视网膜自发复位:病例报告

Spontaneous Retinal Reattachment following Multiple Vitreoretinal Interventions: Case Report.

作者信息

Wise Nathan Nash, Chin Eric K, Almeida David R P

机构信息

State University of New York, Upstate Medical University, Syracuse, NY, USA.

Retina Consultants of Southern California, Redlands, CA, USA.

出版信息

Case Rep Ophthalmol. 2024 Aug 23;15(1):663-668. doi: 10.1159/000540346. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

The aim of the study was to document and analyze a rare case of spontaneous retinal reattachment in a patient after successive unsuccessful vitreoretinal surgeries and to explore potential mechanisms contributing to this unexpected outcome.

CASE PRESENTATION

A 61-year-old patient with a history of high myopia presented with a rhegmatogenous retinal detachment. After undergoing multiple vitreoretinal procedures, including pars plana vitrectomy with silicone oil tamponade, anatomical reattachment was not achieved, and the patient developed complex retinal detachment associated with myopic foveoschisis. Surprisingly, spontaneous reattachment of the retina was observed during routine follow-up. Comprehensive ocular examination, optical coherence tomography (OCT), and fundus autofluorescence imaging were utilized to confirm and document the retinal status. A thorough review of patient history, surgical reports, and postoperative imaging was performed to discern potential contributory factors. The patient's retina remained attached for 12 months after the last intervention without additional surgical or medical treatment. OCT images revealed normalization of retinal architecture with reestablishment of the foveal contour and partial recovery of visual acuity. No signs of proliferative vitreoretinopathy or other commonly associated complications were observed. Immunological assays and genetic testing ruled out systemic conditions that could predispose to spontaneous reattachment.

CONCLUSION

This case represents a remarkable instance of spontaneous retinal reattachment without surgical intervention after multiple failed procedures. The mechanisms underlying this phenomenon remain speculative; however, they may involve delayed postoperative cellular proliferation and migration, subtle intraocular pressure changes, or unrecognized vitreous traction resolution. Further investigation into similar cases may provide insights into the natural history of retinal detachment and potential self-resolving dynamics, which could inform future therapeutic strategies.

摘要

引言

本研究的目的是记录和分析一名患者在连续多次玻璃体视网膜手术失败后发生的罕见自发性视网膜复位病例,并探讨导致这一意外结果的潜在机制。

病例介绍

一名61岁有高度近视病史的患者出现孔源性视网膜脱离。在接受了包括玻璃体切除联合硅油填充在内的多次玻璃体视网膜手术之后,未能实现解剖复位,并且患者出现了与近视性黄斑劈裂相关的复杂性视网膜脱离。令人惊讶的是,在常规随访期间观察到视网膜自发复位。利用全面的眼部检查、光学相干断层扫描(OCT)和眼底自发荧光成像来确认和记录视网膜状态。对患者病史、手术报告和术后影像进行了全面回顾,以辨别潜在的促成因素。在最后一次干预后,患者的视网膜在未进行额外手术或药物治疗的情况下保持复位状态12个月。OCT图像显示视网膜结构正常化,黄斑轮廓重新建立,视力部分恢复。未观察到增殖性玻璃体视网膜病变或其他常见相关并发症的迹象。免疫测定和基因检测排除了可能导致自发复位的全身性疾病。

结论

本病例代表了一个在多次手术失败后未经手术干预而发生自发性视网膜复位的显著实例。这一现象背后的机制仍属推测;然而,它们可能涉及术后延迟的细胞增殖和迁移、细微的眼压变化或未被识别的玻璃体牵拉解除。对类似病例的进一步研究可能会为视网膜脱离的自然病程和潜在的自我缓解动态提供见解,从而为未来的治疗策略提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ab6/11521428/f5862473a04e/cop-2024-0015-0001-540346_F01.jpg

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