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NovoSorb BTM在创伤重建中的应用:实例及拟议的决策工具

The Use of NovoSorb BTM for Trauma Reconstruction: Illustrative Cases and a Proposed Decision-making Tool.

作者信息

Hendrickson Susan A, Flod Sara, Misky Adam T, Senarath-Yapa Kshemendra, Hettiaratchy Shehan

机构信息

From the Department of Plastic Surgery, Imperial College Healthcare NHS Trust, London, United Kingdom.

出版信息

Plast Reconstr Surg Glob Open. 2024 Oct 28;12(10):e6246. doi: 10.1097/GOX.0000000000006246. eCollection 2024 Oct.

Abstract

Achieving a functional and aesthetic reconstruction following complex trauma is a challenge. Skin substitutes, including acellular dermal matrices, and newer, synthetic options such as NovoSorb biodegradable temporizing membrane (BTM) have given the reconstructive surgeon a useful tool where autologous options have been exhausted, are inappropriate, or would present a suboptimal reconstruction. This case series describes 6 patients admitted to an urban level I major trauma center between July and December 2022. All patients underwent complex reconstructive lower limb surgery using BTM as either a primary or salvage option. In each case, this approach was chosen on a case-by-case basis where it was felt BTM would offer a reconstructive advantage, or where primary reconstructive options had been exhausted. Data were collected retrospectively from case notes. Three patients received BTM as a primary reconstructive option. BTM integrated successfully in all 3. Three patients received BTM as a salvage option. In 1, the exposed fracture site was successfully bridged, and in another, BTM was successfully reapplied over exposed fracture site where BTM had previously failed to incorporate. Although BTM is a relatively new tool in the reconstructive surgeon's armamentarium, requiring further research into long-term outcomes, cost-effectiveness, and patient satisfaction, it can be a useful and versatile tool.

摘要

在复杂创伤后实现功能和美学重建是一项挑战。皮肤替代物,包括脱细胞真皮基质,以及更新的合成材料,如诺沃索布生物可降解临时膜(BTM),为重建外科医生提供了一种有用的工具,当自体选择已用尽、不合适或会导致重建效果不佳时。本病例系列描述了2022年7月至12月期间入住城市一级主要创伤中心的6例患者。所有患者均使用BTM作为主要或挽救性选择进行了复杂的下肢重建手术。在每种情况下,这种方法都是根据具体情况选择的,即认为BTM会提供重建优势,或者主要重建选择已用尽。数据是从病例记录中回顾性收集的。3例患者将BTM作为主要重建选择。BTM在所有3例中均成功整合。3例患者将BTM作为挽救性选择。其中1例,暴露的骨折部位成功桥接,另一例,在BTM先前未能整合的暴露骨折部位成功重新应用了BTM。尽管BTM在重建外科医生的工具库中是一种相对较新的工具,需要对长期结果、成本效益和患者满意度进行进一步研究,但它可以是一种有用且通用的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b45/11519400/f05ed73d8e88/gox-12-e6246-g001.jpg

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