新型冠状病毒感染后再次感染的风险及慢性症状的发生率
Risk of Reinfection and Incidence of Chronic Symptoms After SARS-CoV-2 Infections.
作者信息
Golding Liam, Watts Allison W, Pitblado Mark, Clemens Felicity, Viñeta Paramo Marina, Shew Jacob, Irvine Michael A, Abu-Raya Bahaa, Goldfarb David M, Mâsse Louise C, Lavoie Pascal M
机构信息
BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
出版信息
Open Forum Infect Dis. 2024 Oct 15;11(10):ofae608. doi: 10.1093/ofid/ofae608. eCollection 2024 Oct.
This study showed that a severe acute respiratory syndrome coronavirus 2 infection reduced the risk of reinfection among vaccinated individuals by 0.50 (95% CI, 0.39-0.64) over a 1-year period, after accounting for unreported infections using avidity-based serology. Reciprocally, chronic symptoms increased from a baseline of 21% (95% CI, 16%-28%) among infection-naïve individuals to 43% (95% CI, 30%-61%) in reinfected individuals.
这项研究表明，在使用基于亲和力的血清学方法对未报告感染情况进行核算后，严重急性呼吸综合征冠状病毒2感染在1年时间内使接种疫苗个体的再次感染风险降低了0.50（95%置信区间，0.39 - 0.64）。相应地，慢性症状在未感染个体中的基线水平为21%（95%置信区间，16% - 28%），而在再次感染个体中增至43%（95%置信区间，30% - 61%）。
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