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应对复杂性:适用于合并起搏器的局限性肺癌的立体定向体部放射治疗

Confronting Complexity: Stereotactic Body Radiation Therapy for Localized Lung Cancer with a Pacemaker.

作者信息

Chahid Malak, El Gouach Hanae, Cherkaoui Jaouad Mohamed Reda, Damou Meriem, Sqalli Houssaini Mohammed, Kouhen Fadila

机构信息

Mohammed VI University of Health Sciences, Casablanca, Morocco.

Department of Radiotherapy, Cheikh Khalifa International University Hospital, Casablanca, Morocco.

出版信息

Case Rep Oncol. 2024 Oct 16;17(1):1166-1173. doi: 10.1159/000540262. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

Lung cancer management in patients with pacemakers presents unique challenges. This report examines the utilization of stereotactic body radiation therapy (SBRT) in such a patient population.

CASE PRESENTATION

A 75-year-old former smoker with a dual-chamber pacemaker presented with inoperable lung adenocarcinoma. SBRT (48 Gy in 4 fractions) was chosen following multidisciplinary consultation and thorough pretreatment evaluation by a rhythmologist to assess pacemaker integrity. Continuous cardiac monitoring during SBRT detected no arrhythmias. Adjuvant therapy consisted of radiotherapy alone due to the patient's health status and limited evidence supporting chemotherapy in this context. At the 18-month follow-up, no cancer recurrence was observed, and regular device checks confirmed pacemaker integrity.

CONCLUSION

This case demonstrates the successful management of inoperable lung adenocarcinoma with SBRT in a patient with a pacemaker. It underscores the significance of interdisciplinary cooperation and careful patient assessment to optimize treatment outcomes in this challenging clinical scenario.

摘要

引言

对于装有起搏器的肺癌患者,肺癌的治疗面临着独特的挑战。本报告探讨了立体定向体部放射治疗(SBRT)在这类患者群体中的应用。

病例介绍

一名75岁的曾吸烟者,装有双腔起搏器,被诊断为无法手术切除的肺腺癌。在多学科会诊以及心律专家进行全面的预处理评估以评估起搏器完整性后,选择了SBRT(48 Gy,分4次照射)。SBRT期间的连续心脏监测未检测到心律失常。由于患者的健康状况以及在这种情况下支持化疗的证据有限,辅助治疗仅包括放疗。在18个月的随访中,未观察到癌症复发,并且定期的设备检查证实起搏器功能正常。

结论

本病例证明了SBRT成功治疗了一名装有起搏器患者的无法手术切除的肺腺癌。它强调了跨学科合作和仔细的患者评估在这种具有挑战性的临床情况下优化治疗结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27e4/11521424/ed1f64dd4643/cro-2024-0017-0001-540262_F01.jpg

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