Leeds Gastroenterology Institute, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Academic Unit for Ageing and Stroke Research, University of Leeds, Bradford Institute for Health Research, Bradford, UK.
J Crohns Colitis. 2024 Oct 30;18(Supplement_2):ii46-ii54. doi: 10.1093/ecco-jcc/jjae067.
There are growing numbers of older people with inflammatory bowel diseases [IBD]. These older patients are more likely to have other comorbidities and polypharmacy, which can make recognizing and treating IBD complex. Frailty is a newer concept in the IBD field, and we are beginning to recognize the importance of this as a marker of biological age and its association with risk of adverse IBD-related outcomes. In this review article we aim to provide practical insight into the specific challenges facing older patients and their clinicians at each stage of the patient journey. We also discuss the latest understanding of the impact of frailty for these patients with IBD and highlight areas for future research.
患有炎症性肠病（IBD）的老年人数量正在增加。这些老年患者更有可能患有其他合并症和多种药物治疗，这使得识别和治疗 IBD 变得复杂。虚弱是 IBD 领域的一个新概念，我们开始认识到它作为生物年龄的标志物及其与不良 IBD 相关结局风险的关联的重要性。在这篇综述文章中，我们旨在为老年患者及其临床医生在患者旅程的每个阶段所面临的具体挑战提供实用的见解。我们还讨论了最新的关于虚弱对这些 IBD 患者的影响的理解，并强调了未来研究的领域。
