Fundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Laboratório Avançado de Saúde Pública, Salvador, BA, Brasil.
Fundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Grupo de Pesquisa Interdisciplinar em Biotecnologia e Epidemiologia de Doenças Infecciosas, Salvador, BA, Brasil.
Mem Inst Oswaldo Cruz. 2024 Oct 28;119:e240140. doi: 10.1590/0074-02760240140. eCollection 2024.
Chagas disease (CD), caused by Trypanosoma cruzi, is a life-threatening neglected anthropozoonosis primarily transmitted by triatomine bugs. Affecting an estimated 5.7 million people globally, CD has significant morbidity and mortality, particularly in Latin America. The Oxente Chagas Bahia Project aims to screen approximately 30,000 individuals, validate a rapid diagnostic test in a real-world setting, and provide crucial data on its diagnostic performance and cost-effectiveness. Additionally, a biobank will be established to support further research on disease biomarkers and treatment cure rates. By enhancing access to timely diagnosis and treatment, the project will evaluate a strategy to reduce the CD burden.
恰加斯病（CD）是由克氏锥虫引起的一种危及生命的被忽视的人兽共患病，主要通过锥蝽传播。据估计，全球有 570 万人受到影响，CD 具有较高的发病率和死亡率，特别是在拉丁美洲。Oxente Chagas Bahia 项目旨在对大约 30000 人进行筛查，在真实环境中验证一种快速诊断测试，并提供关于其诊断性能和成本效益的重要数据。此外，还将建立一个生物银行，以支持进一步研究疾病生物标志物和治疗治愈率。通过提高及时诊断和治疗的可及性，该项目将评估一种降低 CD 负担的策略。
