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评估绞窄性腹股沟疝修补术中补片修补的安全性:一项系统评价和荟萃分析。

Assessing the Safety of Mesh Repair in Strangulated Groin Hernias: A Systematic Review and Meta-Analysis.

作者信息

Ekwesianya Andrew C, Ayantunde Abraham, Nour Hussameldin M

机构信息

Department of General and Colorectal Surgery, Southend University Hospital, Southend, GBR.

Department of General Surgery, Royal Lancaster Infirmary, Lancaster, GBR.

出版信息

Cureus. 2024 Sep 30;16(9):e70496. doi: 10.7759/cureus.70496. eCollection 2024 Sep.

Abstract

The use of mesh in emergency repair of complicated groin hernias has been a subject of discussion for decades. While it is now generally accepted that mesh could safely be used in incarcerated (irreducible) and obstructed hernias (without strangulation), with wound infection rates comparable to suture repairs, the use of mesh in strangulated hernias involving bowel resection is still controversial. The aim of this study, therefore, was to analyse the safety of mesh use in strangulated hernias with ischaemic bowel at the time of surgery. A literature search was carried out using relevant keywords. The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 framework anddata analysis was done using the Review Manager version 5.4 (The Cochrane Collaboration, Oxford, UK) meta-analysis software. Seven studies comprising 1,159 patients who had emergency surgery for strangulated groin hernias were analysed. A pooled random effect meta-analysis did not show any significant difference in the surgical site infection rate (odds ratio (OR) = 0.88, 95% confidence interval (CI) = 0.39-1.96, p = 0.75), seroma formation (OR = 3.39; 95% CI = 0.70-16.43; p = 0.13), and hernia recurrence (OR = 0.33; CI = 0.05-2.22; p = 0.26) between the two groups. The long-held concern that mesh could not be safely used in strangulated groin hernias has not been validated by the results obtained from this systematic review and meta-analysis. However, more randomised controlled trials in this clinical area would need to be carried out to further validate the results of this study.

摘要

几十年来,在复杂腹股沟疝的急诊修补中使用补片一直是一个讨论的话题。虽然现在普遍认为补片可安全用于嵌顿(不可复性)和梗阻性疝(无绞窄),其伤口感染率与缝合修补相当,但在涉及肠切除的绞窄性疝中使用补片仍存在争议。因此,本研究的目的是分析在手术时对伴有肠缺血的绞窄性疝使用补片的安全性。使用相关关键词进行了文献检索。本研究按照系统评价和Meta分析的首选报告项目(PRISMA)2020框架进行,数据分析使用Review Manager 5.4版(英国牛津Cochrane协作网)Meta分析软件。分析了7项研究,共1159例因绞窄性腹股沟疝接受急诊手术的患者。汇总随机效应Meta分析显示,两组在手术部位感染率(比值比(OR)=0.88,95%置信区间(CI)=0.39 - 1.96,p = 0.75)、血清肿形成(OR = 3.39;95% CI = 0.70 - 16.43;p = 0.13)和疝复发(OR = 0.33;CI = 0.05 - 2.22;p = 0.26)方面均无显著差异。长期以来关于补片不能安全用于绞窄性腹股沟疝的担忧并未得到该系统评价和Meta分析结果的证实。然而,需要在该临床领域开展更多随机对照试验以进一步验证本研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/234a/11523024/577b583f9a11/cureus-0016-00000070496-i01.jpg

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