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网片修补与非网片修补治疗嵌顿性和绞窄性腹股沟疝:更新的系统评价和荟萃分析。

Mesh repair versus non-mesh repair for incarcerated and strangulated groin hernia: an updated systematic review and meta-analysis.

机构信息

School of Medicine, Universidade Federal da Fronteira Sul, 20 Capitão Araújo St, Passo Fundo, RS, 99010121, Brazil.

Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA.

出版信息

Hernia. 2023 Dec;27(6):1397-1413. doi: 10.1007/s10029-023-02874-0. Epub 2023 Sep 7.

Abstract

BACKGROUND

Mesh repair in incarcerated or strangulated groin hernia is controversial, especially when bowel resection is required. We aimed to perform a meta-analysis comparing mesh and non-mesh repair in patients undergoing emergency groin hernia repair.

METHODS

We performed a literature search of databases to identify studies comparing mesh and primary suture repair of patients with incarcerated or strangulated inguinal or femoral hernias who underwent emergency surgery. Postoperative outcomes were assessed by pooled analysis and meta-analysis. Statistical analysis was performed using RevMan 5.4. Heterogeneity was assessed with I statistics.

RESULTS

1095 studies were screened and 101 were thoroughly reviewed. Twenty observational studies and four randomized controlled trials comprising 12,402 patients were included. We found that mesh-based repair had reduced recurrence (OR 0.36; 95% CI 0.19, 0.67; P = 0.001; I = 35%), length of hospital stay (OR - 1.02; 95% CI - 1.87, - 0.17; P = 0.02; I = 94%) and operative time (OR - 9.21; 95% CI - 16.82, - 1.61; P = 0.02; I = 95%) without increasing surgical site infection, mortality or postoperative complications such as seroma, chronic, ileus or urinary retention. In the subgroup analysis of patients that underwent bowel resection, we found that mesh repair was associated with an increased risk of surgical site infection (OR 1.74; 95% CI 1.04, 2.91; P = 0.04; I = 9%).

CONCLUSIONS

Mesh repair for incarcerated and strangulated groin hernias reduces recurrence without an increase in postoperative complications and should be considered in clean cases. However, in the setting of bowel resection, mesh repair might increase the incidence of surgical site infection.

摘要

背景

在嵌顿或绞窄性腹股沟疝中使用补片修复存在争议,尤其是在需要进行肠切除术时。我们旨在进行一项荟萃分析,比较接受紧急腹股沟疝修复的患者中使用补片与非补片修复的效果。

方法

我们对数据库进行了文献检索,以确定比较嵌顿或绞窄性腹股沟或股疝患者在接受紧急手术时使用补片与初次缝合修复的研究。通过汇总分析和荟萃分析评估术后结局。使用 RevMan 5.4 进行统计分析。使用 I ² 统计量评估异质性。

结果

筛选出 1095 项研究并对其中 101 项进行了详细审查。纳入了 20 项观察性研究和 4 项随机对照试验,共 12402 名患者。我们发现,基于补片的修复可以降低复发率(OR 0.36;95%CI 0.19,0.67;P=0.001;I²=35%)、住院时间(OR -1.02;95%CI -1.87,-0.17;P=0.02;I²=94%)和手术时间(OR -9.21;95%CI -16.82,-0.17;P=0.02;I²=95%),而不会增加手术部位感染、死亡率或术后并发症,如血清肿、慢性、肠梗阻或尿潴留。在对接受肠切除术的患者进行的亚组分析中,我们发现补片修复与手术部位感染的风险增加相关(OR 1.74;95%CI 1.04,2.91;P=0.04;I²=9%)。

结论

对于嵌顿和绞窄性腹股沟疝,使用补片修复可以降低复发率,而不会增加术后并发症,在清洁病例中应考虑使用。然而,在肠切除术的情况下,补片修复可能会增加手术部位感染的发生率。

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