Begum N Fazulunnisa, Ramalingam Karthikeyan, Ramani Pratibha, M Arun
Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Sep 30;16(9):e70514. doi: 10.7759/cureus.70514. eCollection 2024 Sep.
Oral plexiform neurofibroma is a benign tumor of the peripheral nerves. It shows multiple nerve bundles with a "plexus" appearance, creating a "bag of worms" texture. They carry higher recurrences and an increased risk of malignant transformation. We present a case of a young male with an oral plexiform neurofibroma in the buccal mucosa. The patient was advised to do a full-body examination to rule out neurofibromatosis. Although surgical excision is the mainstay of treatment for oral plexiform neurofibromas, the recurrence rate could be high. The present case report aims to explore the potential mechanisms underlying recurrences even after what is considered a complete surgical removal. The involvement of critical anatomical structures may limit the extent of excision. Understanding the exact pathogenesis of recurrence is essential for improving surgical outcomes and developing more effective management.
口腔丛状神经纤维瘤是一种周围神经的良性肿瘤。它表现为多个具有“丛状”外观的神经束，形成“虫袋”样质地。它们具有较高的复发率和恶性转化风险。我们报告一例年轻男性颊黏膜发生口腔丛状神经纤维瘤的病例。建议患者进行全身检查以排除神经纤维瘤病。虽然手术切除是口腔丛状神经纤维瘤的主要治疗方法，但复发率可能较高。本病例报告旨在探讨即使在被认为是完整手术切除后仍复发的潜在机制。关键解剖结构的累及可能会限制切除范围。了解复发的确切发病机制对于改善手术效果和制定更有效的治疗方案至关重要。
