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食管癌和胃癌患者经空肠造口管饲进行营养支持:基于现有证据提出通用工作策略

Nutritional support via feeding jejunostomy in esophago-gastric cancers: proposal of a common working strategy based on the available evidence.

作者信息

Caccialanza Riccardo, Da Prat Valentina, De Luca Raffaele, Weindelmayer Jacopo, Casirati Amanda, De Manzoni Giovanni

机构信息

Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Department of Surgical Oncology, IRCCS-Istituto Tumori "Giovanni Paolo II, Bari, Italy.

出版信息

Updates Surg. 2025 Jan;77(1):153-164. doi: 10.1007/s13304-024-02022-y. Epub 2024 Oct 31.

Abstract

Malnutrition is common in patients affected by esophago-gastric cancers and has a negative impact on both clinical and economic outcomes. Yet not all patients at risk of malnutrition are routinely assessed and receive appropriate support. Further, available research does not provide a mean for standardization of timing, route, and dosage for nutritional support, and this is particularly true for enteral nutrition via feeding jejunostomy. Herein, we provide an overview of the current evidence and use the gathered knowledge as a starting point for a consensus proposal. As a result, we aim to facilitate the development of appropriate and uniformed interventions, thus fulfilling the need for a multimodal therapeutic approach in these set of cancer patients.

摘要

营养不良在食管癌和胃癌患者中很常见,对临床和经济结局均有负面影响。然而,并非所有有营养不良风险的患者都能得到常规评估并获得适当的支持。此外,现有研究并未提供营养支持的时间、途径和剂量标准化方法,经空肠造口管饲的肠内营养尤其如此。在此,我们概述当前证据,并以所收集的知识为基础提出共识建议。因此,我们旨在促进制定适当且统一的干预措施,从而满足这类癌症患者对多模式治疗方法的需求。

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