Han Yunmin, Choi Younghwan, Kim Yeon Soo
Seoul National University, Seoul, Republic of Korea.
Institute of Sports Science, Seoul National University, Seoul, Republic of Korea.
Clin Hypertens. 2024 Nov 1;30(1):30. doi: 10.1186/s40885-024-00291-8.
In Korea, chronic kidney disease (CKD) is increasingly prevalent among adults with hypertension, of which approximately 30% of the population is affected. Despite the recognized benefits of adherence to physical activity (PA) recommendations, including aerobic and muscle-strengthening activities (MSA), the impact of such adherence on the prevalence of CKD in individuals with hypertension has not been extensively studied. This study aimed to investigate the association between aerobic PA and MSA levels, and the prevalence of CKD in individuals with hypertension.
This study included 5,078 individuals with hypertension using data from the Korean National Health and Nutrition Examination Survey (2019-2021). PA levels were measured as min/week of moderate-to-vigorous PA (MVPA) based on self-reports, and MSA was quantified as the number of days per week. CKD was defined as an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m². Logistic regression analysis evaluated the association between meeting PA guidelines and CKD after adjusting for potential confounders. Additionally, a joint analysis was conducted to assess the combined effects of MVPA and MSA on CKD.
After adjusting for all covariates, higher MVPA was associated with a lower prevalence of CKD. Compared to the group with inactive, the group with MVPA 1-149 min/week had an odds ratio (OR) of 0.80 (95% confidence interval [CI], 0.61-1.05), the group that met the MVPA 150-299 min/week criteria had an OR of 0.85 (95% CI, 0.62-1.17), and the group that met the MVPA ≥ 300 min/week criteria had an OR of 0.53 (95% CI, 0.37-0.76). MSA alone did not show a significant association with CKD. In the joint analysis, the group that met the MVPA and MSA guidelines had the lowest OR of 0.54 (95% CI, 0.34-0.86), compared to the group that did not meet either.
MVPA was associated with the prevalence of CKD in participants with hypertension but not in those with MSA alone. However, compared with the group that did not meet both guidelines, the group that met both guidelines showed the lowest prevalence of CKD.
在韩国，慢性肾脏病（CKD）在患有高血压的成年人中越来越普遍，约30%的人口受到影响。尽管人们认识到坚持体育活动（PA）建议（包括有氧运动和肌肉强化活动（MSA））有诸多益处，但这种坚持对高血压患者CKD患病率的影响尚未得到广泛研究。本研究旨在调查有氧运动PA和MSA水平与高血压患者CKD患病率之间的关联。
本研究纳入了5078名高血压患者，使用韩国国家健康与营养检查调查（2019 - 2021年）的数据。PA水平根据自我报告以中度至剧烈PA（MVPA）的分钟数/周来衡量，MSA则量化为每周的天数。CKD定义为估计肾小球滤过率（eGFR）<60 mL/min/1.73 m²。逻辑回归分析在调整潜在混杂因素后评估达到PA指南与CKD之间的关联。此外，进行了联合分析以评估MVPA和MSA对CKD的综合影响。
在调整所有协变量后，较高的MVPA与较低的CKD患病率相关。与不活动组相比，MVPA为1 - 149分钟/周的组的比值比（OR）为0.80（95%置信区间[CI]，0.61 - 1.05），达到MVPA 150 - 299分钟/周标准的组的OR为0.85（95% CI，0.62 - 1.17），达到MVPA≥300分钟/周标准的组的OR为0.53（95% CI，0.37 - 0.76）。单独的MSA与CKD没有显著关联。在联合分析中，与未达到任何一项指南的组相比，达到MVPA和MSA指南的组的OR最低，为0.54（95% CI，0.34 - 0.86）。
MVPA与高血压患者的CKD患病率相关，但单独的MSA则不然。然而，与未达到两项指南的组相比，达到两项指南的组的CKD患病率最低。
