Graves B Sue, Patel Mitsu, Newgent Hailey, Parvathy Gauri, Nasri Ahmad, Moxam Jillene, Gill Gurnoor S, Sawhney Vivek, Gupta Manish
Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, USA.
Medicine, Smt. Nathiba Hargovandas Lakhmichand Municipal Medical College, Ahmedabad, IND.
Cureus. 2024 Oct 1;16(10):e70616. doi: 10.7759/cureus.70616. eCollection 2024 Oct.
Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a complex, chronic condition marked by persistent, debilitating fatigue that is not alleviated by rest and often worsens with physical or mental exertion. Along with fatigue, patients experience various symptoms, including cognitive impairments, post-exertional malaise, muscle and joint pain, sleep disturbances, and immune system dysfunction. Diagnosing CFS/ME is challenging due to the absence of definitive biomarkers, the overlap of symptoms with other conditions, and the lack of standardized diagnostic criteria. This comprehensive literature review aims to contribute to the understanding of CFS/ME, including its diagnosis, pathophysiology, differential diagnosis, treatment, and future directions.
肌痛性脑脊髓炎（ME），也称为慢性疲劳综合征（CFS），是一种复杂的慢性疾病，其特征是持续存在、使人衰弱的疲劳，休息不能缓解，且体力或脑力活动后往往会加重。除疲劳外，患者还会出现各种症状，包括认知障碍、劳累后不适、肌肉和关节疼痛、睡眠障碍以及免疫系统功能障碍。由于缺乏明确的生物标志物、症状与其他疾病的重叠以及缺乏标准化的诊断标准，CFS/ME的诊断具有挑战性。这篇全面的文献综述旨在促进对CFS/ME的理解，包括其诊断、病理生理学、鉴别诊断、治疗以及未来方向。
