Aytekin Bahadır, Akkaya Bekir Boğaçhan, Mavioğlu Hayrettin Levent, İşcan Hakkı Zafer
Department of Cardiovascular Surgery, Ankara Bilkent City Hospital, 06800 Ankara, Turkey.
Rev Cardiovasc Med. 2024 Oct 10;25(10):363. doi: 10.31083/j.rcm2510363. eCollection 2024 Oct.
The incidence of late open surgical conversions (OSCs) has recently increased. Vascular surgeons face additional technical challenges in late conversion surgery of failed endovascular aneurysm repair (EVAR) due to the presence of a previously deployed endograft. Based on our institutional experience, this study aimed to delineate methods to improve late open conversion outcomes, proposing solutions for technical challenges.
All preoperative OSC data on failed EVARs operated in our Cardiovascular Surgery Clinic between January 2017 and January 2024 were evaluated retrospectively. Study endpoints included early (30-day or in-hospital) and late follow-up outcomes. Early outcomes included perioperative mortality and morbidities, intensive care unit (ICU) period, and length of hospital stay (LOS). The main outcome of interest during follow-up was overall survival.
Sixteen patients in our hospital, comprising eight elective and eight emergency procedures, underwent OSCs following EVAR. The difference between the 30-day mortality rates for the elective and urgent late conversions was significant ( < 0.001). Of these patients, 15 were male, with a mean age of 70.8 years (range: 62-80). Preoperative cardiac shock status and low hematocrit level (<20%) were independent mortality factors ( < 0.001). The ICU period was 8.7 ± 5.3 days (2-20 days) on average, and LOS was 17.3 ± 8.4 (6-29 days) days on average. The mean time to open surgical conversion in this cohort was 44.4 ± 16.8 months. The 5-year overall survival rate was 43.75%.
The incidence of open surgical conversion is notably growing. Emergent open surgical conversions exhibit poorer mortality outcomes compared to elective procedures. Further data are essential to evaluate the ramifications of expanding the use of EVAR beyond the instructions for use (IFU) guidelines. The procedures involving patients who challenge the IFU criteria should be conducted at experienced centers and require close monitoring. Open surgical repair (OSR) as the initial treatment opportunity could be an alternative strategy for improving outcomes in this patient cohort.
近期晚期开放手术转换(OSC)的发生率有所增加。由于先前已植入的血管内支架移植物的存在,血管外科医生在失败的血管内动脉瘤修复术(EVAR)的晚期转换手术中面临额外的技术挑战。基于我们机构的经验,本研究旨在阐明改善晚期开放转换结局的方法,针对技术挑战提出解决方案。
回顾性评估2017年1月至2024年1月期间在我们心血管外科诊所接受手术的失败EVAR的所有术前OSC数据。研究终点包括早期(30天或住院期间)和晚期随访结局。早期结局包括围手术期死亡率和发病率、重症监护病房(ICU)住院时间以及住院时长(LOS)。随访期间关注的主要结局是总体生存率。
我院16例患者接受了EVAR术后的OSC,其中包括8例择期手术和8例急诊手术。择期和紧急晚期转换的30天死亡率差异显著(<0.001)。这些患者中,15例为男性,平均年龄70.8岁(范围:62 - 80岁)。术前心源性休克状态和低血细胞比容水平(<20%)是独立的死亡因素(<0.001)。ICU平均住院时间为8.7±5.3天(2 - 20天),LOS平均为17.3±8.4天(6 - 29天)。该队列中开放手术转换的平均时间为44.4±16.8个月。5年总体生存率为43.75%。
开放手术转换的发生率显著上升。与择期手术相比,急诊开放手术转换的死亡率结局更差。进一步的数据对于评估超出使用说明(IFU)指南扩大EVAR使用的影响至关重要。涉及挑战IFU标准患者的手术应在经验丰富的中心进行,并需要密切监测。开放手术修复(OSR)作为初始治疗机会可能是改善该患者群体结局的替代策略。