免疫检查点的空间背景是独立于标准肿瘤-淋巴结-转移分期预测可切除结直肠癌患者总生存期的因素。
Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor-Node-Metastasis Stages.
机构信息
Department of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Laboratory of Digestive Surgery, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China.
出版信息
Cancer Res Commun. 2024 Nov 1;4(11):3025-3035. doi: 10.1158/2767-9764.CRC-24-0270.
Abstract
The identification of specific spatial patterns of immune checkpoint expression that correlate with overall survival in patients with colon cancer suggests a potential prognostic tool for risk stratification and treatment selection. These findings pave the way for the development of novel therapeutic strategies to enhance antitumor immune responses.
摘要
鉴定与结肠癌患者总生存期相关的特定免疫检查点表达的空间模式，提示了一种用于风险分层和治疗选择的潜在预后工具。这些发现为开发增强抗肿瘤免疫反应的新治疗策略铺平了道路。
Zotero 插件