重新定义促进胃癌发生的胃微生物群：非幽门螺杆菌微生物组的兴起。

Redefining the Gastric Microbes in Promoting Gastric Tumorigenesis: The Rise of the Non-H. pylori Microbiome.

机构信息

State Key Laboratory of Digestive Disease, Department of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.

出版信息

Cancer Discov. 2024 Nov 1;14(11):2051-2054. doi: 10.1158/2159-8290.CD-24-0835.

DOI:10.1158/2159-8290.CD-24-0835

Abstract

Gastric cancer remains one of the top cancers in China compared with Western countries, mainly attributed to the high rates of Helicobacter pylori infection. However, recent discoveries on the non-H. pylori gastric microbiome have led to a paradigm shift in our understanding of microbial risk factors driving gastric cancer, which will impact future screening and prevention strategies.

摘要

与西方国家相比，胃癌仍然是中国最常见的癌症之一，主要归因于幽门螺杆菌感染率高。然而，最近对非幽门螺杆菌胃微生物组的发现，导致了我们对微生物危险因素导致胃癌的认识发生了范式转变，这将影响未来的筛查和预防策略。