Guilleminault C, Motta J, Mihm F, Melvin K
Chest. 1986 Mar;89(3):331-4. doi: 10.1378/chest.89.3.331.
Seventeen men (age range, 21 to 58 years) with severe obstructive sleep apnea syndrome (OSAS) documented by nocturnal polysomnography underwent hemodynamic investigations during sleep. We studied the evolution of the cardiac index during apneic events in both NREM and REM sleep using the thermodilution technique. Regardless of the patient's age, the sleep state, or the mechanism inducing the OSAS, the cardiac index decreased significantly from baseline during an apneic event and increased significantly from baseline at the resumption of ventilation.
17名男性（年龄范围为21至58岁），经夜间多导睡眠图记录证实患有严重阻塞性睡眠呼吸暂停综合征（OSAS），在睡眠期间接受了血流动力学检查。我们使用热稀释技术研究了非快速眼动（NREM）睡眠和快速眼动（REM）睡眠中呼吸暂停事件期间心脏指数的变化。无论患者的年龄、睡眠状态或导致OSAS的机制如何，在呼吸暂停事件期间心脏指数均较基线显著下降，而在恢复通气时较基线显著升高。
