Pediatric Infectious Disease, Department of Pediatrics, Renaissance School of Medicine, State University of New York at Stony Brook, 101 Nicholls Road, Stony Brook, NY 11794-8111, USA.
Clin Perinatol. 2024 Dec;51(4):935-949. doi: 10.1016/j.clp.2024.08.009. Epub 2024 Sep 20.
The clinical trial networks that included a maternal-child focus have evolved since first funded by NIH in the 1990s. Since then, US domestic and international sites were combined into one network, with a focused agenda on therapeutics (for both prevention and treatment), human immunodeficiency virus (HIV) cure, tuberculosis, and complications of HIV, largely specific to the brain. Key to the success of the network has been a strong partnership with the community, collaborations with industry and other strategic partners, and recognition that one size does not fit all when it comes to antiretrovirals, diagnosing and treating TB, and other treatments for our populations.
自 20 世纪 90 年代首次由美国国立卫生研究院（NIH）资助以来，包含母婴重点的临床试验网络已经发展。从那时起，美国国内和国际的试验点合并成一个网络，重点关注治疗方法（包括预防和治疗）、人类免疫缺陷病毒（HIV）治愈、结核病和 HIV 并发症，主要针对大脑。该网络的成功关键在于与社区建立了强有力的伙伴关系，与行业和其他战略伙伴合作，并认识到在抗逆转录病毒药物、诊断和治疗结核病以及针对我们人群的其他治疗方面，一刀切并不适用。
