Matek W, Hermanek P, Demling L
Endoscopy. 1986 Jan;18(1):17-9. doi: 10.1055/s-2007-1018314.
This article takes a look at the different localisation of colorectal adenomas and carcinomas. The risk of malignancy of 4,257 adenomas found in 1742 patients was determined, and the lesions grouped in accordance with various criteria and risk classes. It was found that the distribution of adenoma locations approximated all the more closely to the distribution pattern of carcinoma sites, the higher the malignancy risk of an adenoma group was. The statistical approximation of adenoma and carcinoma localisations as a function of increasing risk of malignancy must be considered an argument in support of the adenoma--carcinoma sequence.
本文探讨了结肠直肠腺瘤和癌的不同定位。确定了1742例患者中发现的4257个腺瘤的恶性风险，并根据各种标准和风险类别对病变进行分组。结果发现，腺瘤组的恶性风险越高，腺瘤位置的分布就越接近癌部位的分布模式。腺瘤和癌定位随恶性风险增加的统计近似关系必须被视为支持腺瘤-癌序列的一个论据。
