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爬楼梯干预可降低餐后高血糖,但对认知功能无影响:一项随机交叉试验的结果

Stair climbing interventions reduce postprandial hyperglycemia but not cognitive functions: findings of a randomized cross-over trial.

作者信息

Thirunavukarasu Eswaran Tpm, Reddy Manaswi, Chandrasekaran Baskaran, Maiya Arun G, Rao Chythra R

机构信息

Department of Exercise and Sports Sciences, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Department of Exercise and Sports Sciences, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

Physiol Behav. 2024 Nov 1:114726. doi: 10.1016/j.physbeh.2024.114726.

DOI:10.1016/j.physbeh.2024.114726
PMID:39489460
Abstract

Prolonged sitting can negatively impact postprandial glucose levels and cognitive functions. Stair climbing interventions have potential to mitigate these risks however remains unexplored. The present study aimed to explore the effects of stair climbing bouts on postprandial glucose and cognitive functions during prolonged sitting. Twenty-eight sedentary young adults (aged 20 - 30 years) underwent two intervention visits after standardized lunch for two hours: (1) STAIR: the participants climbed two flight of stairs for two minutes every 30 minutes; (2) SIT: the participants continued to sit. Blood glucose was measured using capillary finger prick method while attention function was measured using computer-based cognitive tests at baseline, end of 1st hour and 2nd hour. Significant interaction (F = 15.96, p <0.001) was observed for conditions and time. During STAIR visit, significant changes in postprandial glucose at 1 hour (β = - 2.6 mmol/dl, p <0.001) and 2 hour (β = 3.0 mmol/dl, p <0.001). No significant difference in the attention functions with time and conditions was observed. Stair climbing interruptions may be a promising solution to prevent high glycemic excursion occurring during prolonged sitting following postprandial sessions. However, the clinical benefits of stair climbing on attention functions remain unconvinced.

摘要

长时间坐着会对餐后血糖水平和认知功能产生负面影响。爬楼梯干预有可能减轻这些风险,但仍有待探索。本研究旨在探讨爬楼梯对餐后长时间坐着期间的餐后血糖和认知功能的影响。28名久坐不动的年轻人(年龄在20 - 30岁之间)在标准化午餐后进行了两小时的两次干预访问:(1)爬楼梯组:参与者每30分钟爬两层楼梯,持续两分钟;(2)坐着组:参与者继续坐着。在基线、第1小时末和第2小时末,使用毛细血管手指刺血法测量血糖,同时使用基于计算机的认知测试测量注意力功能。观察到条件和时间之间存在显著交互作用(F = 15.96,p < 0.001)。在爬楼梯访问期间,餐后1小时(β = - 2.6 mmol/dl,p < 0.001)和2小时(β = 3.0 mmol/dl,p < 0.001)的血糖有显著变化。未观察到注意力功能随时间和条件的显著差异。爬楼梯中断可能是预防餐后长时间坐着期间发生高血糖波动的一个有前景的解决方案。然而,爬楼梯对注意力功能的临床益处仍未得到证实。

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