Lomtadze D M, Tsorin I B, Chirkova E Iu, Chichkanov G G
Farmakol Toksikol. 1990 Mar-Apr;53(2):31-4.
In experiments on anesthetized cats with acute occlusion of the coronary artery followed by its reperfusion antihypoxants piracetam, lithium hydroxybutyrate and pyrid oxynyl-glyoxylate (glyo-6) were shown to stabilize the contractile and pumping functions of the heart. GABA derivatives piracetam and lithium hydroxybutyrate in contrast to glyo-6 were found not only to stimulate the compensatory processes in the conventional intact area of the ischemized left ventricle but also improve the energy metabolism in the ischemic focus itself.
在对冠状动脉急性闭塞后再灌注的麻醉猫进行的实验中，已表明抗缺氧剂吡拉西坦、羟基丁酸钠和吡啶氧基乙醛酸（glyo-6）可稳定心脏的收缩和泵血功能。与glyo-6不同，吡拉西坦和羟基丁酸钠这两种GABA衍生物不仅能刺激缺血左心室传统完整区域的代偿过程，还能改善缺血灶本身的能量代谢。
